In the current study, an environmental assessment of surface seawater in Tangier Bay was conducted by analyzing physicochemical parameters and trace elements, such as As, Cr, Zn, Cd, Pb, and Cu. The results showed mean concentrations (μg/l) of 22.50 for As, 0.46 for Cr, 8.57 for Zn, 15.41 for Cd, 0.23 for Pb, and 1.83 for Cu. While most trace elements met the guidelines, elevated levels of Cd raised concerns about long-term exposure. Pollution indices, including the contamination factor, degree of contamination, and water quality index, indicate the impact of human activities, dividing sites into arsenic-cadmium contamination, wastewater influence, and low pollution levels. Statistical methods, such as ANOVA, revealed no significant differences in trace element levels across the bay. PCA and HCA revealed that Cr, Cu, and Zn originated from common anthropogenic sources, whereas Pb and Cd originated from distinct sources. As indicates that natural geological processes influence its origin.
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http://dx.doi.org/10.1016/j.marpolbul.2024.116362 | DOI Listing |
In Vivo
December 2024
College of Biology, Hunan University, Changsha, P.R. China;
Background/aim: Silicosis, the most severe type of occupational pneumoconiosis, leads to diffuse pulmonary fibrosis without specific therapy. Ferroptosis is triggered by reactive oxygen species (ROS) and Fe overload-induced lipid peroxidation, which is involved in the progression of pulmonary fibrosis. As an important coenzyme in the process of aerobic respiration, Coenzyme Q10 (CoQ10) can enhance mitochondrial function and energy supply and reduce malondialdehyde (MDA) to limit the risk of fibrosis.
View Article and Find Full Text PDFSci Total Environ
December 2024
Institute of Mountain Hazards and Environment, Chinese Academy of Sciences, Chengdu 610299, China. Electronic address:
The elemental dynamics and interactions within deadwood profoundly influence carbon sequestration and nutrient cycling in forest ecosystems. Recent studies have investigated macronutrient cycling during deadwood decay of specific plants, yet the dynamics and interactions of micronutrients, trace elements, and the elementome across species and decay stages remain unexplored. Here, we investigated the elementome and their coupling relationships across five decay stages of downed deadwood (DDW) from four dominant species (Hippophae rhamnoides, Populus purdomii, Abies fabri, and Picea brachytyla) along the Hailuogou Glacier primary successional chronosequence.
View Article and Find Full Text PDFPLoS One
December 2024
Ningbo Medical Center Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, People's Republic of China.
Background: The evolution of NAFLD, MAFLD, and MASLD underscores significant advancements and nomenclatural shifts in the realm of chronic liver disorders. This study primarily aimed to investigate the possible link between serum selenium levels and the occurrence of MASLD.
Methods: Utilizing data from NHANES for the years 2017 through 2020, we performed an in-depth analysis.
Proc Natl Acad Sci U S A
January 2025
Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095.
To successfully mount infections, nearly all bacterial pathogens must acquire iron, a key metal cofactor that primarily resides within human hemoglobin. causes the life-threatening respiratory disease diphtheria and captures hemoglobin for iron scavenging using the surface-displayed receptor HbpA. Here, we show using X-ray crystallography, NMR, and in situ binding measurements that selectively captures iron-loaded hemoglobin by partially ensconcing the heme molecules of its α subunits.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Departments of Molecular Biosciences and of Chemistry, Northwestern University, Evanston, IL 60208.
Methane- and ammonia-oxidizing bacteria play key roles in the global carbon and nitrogen cycles, respectively. These bacteria use homologous copper membrane monooxygenases to accomplish the defining chemical transformations of their metabolisms: the oxidations of methane to methanol by particulate methane monooxygenase (pMMO) and ammonia to hydroxylamine by ammonia monooxygenase (AMO), enzymes of prime interest for applications in mitigating climate change. However, investigations of these enzymes have been hindered by the need for disruptive detergent solubilization prior to structure determination, confounding studies of pMMO and precluding studies of AMO.
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