AI Article Synopsis

  • Traditional intrathecal analgesic treatments are insufficient for managing severe craniofacial pain, prompting the development of a new technique for drug delivery via spinal puncture and catheterization in the intra-prepontine cistern.* -
  • A modified Delphi method involving expert consultations led to a consensus on key aspects of the intra-prepontine cisternal drug delivery technique, including principles, indications, and patient management, with over 80% agreement on seven topics.* -
  • This new technique is considered minimally invasive and effective, potentially improving the quality of life for patients with refractory pain, and highlights the need for standardized practices in its application across medical fields.*

Article Abstract

Objectives: The distribution characteristics of intrathecal drugs and the limitation of current catheterization techniques make traditional intrathecal analgesic treatment nearly useless for refractory craniofacial pain, such as trigemina neuralgia. This technical guideline aims to promote the widespread and standardize the application of intra-prepontine cisternal drug delivery via spinal puncture and catheterization.

Methods: A modified Delphi approach was used to work for this guideline. On the issues related to the intra-prepontine cisternal targeted drug delivery technique, the working group consulted 10 experts from the field with 3 rounds of email feedback and 3 rounds of conference discussion.

Results: For the efficacy and safety of the intra-prepontine cisternal targeted drug delivery technique, a consensus was formed on 7 topics (with an agreement rate of more than 80%), including the principles of the technique, indications and contraindications, patient preparation, surgical specifications for intra-prepontine cisternal catheter placement, analgesic dosage coordination, analgesic management, and prevention and treatment of complications.

Conclusions: Utilizing the intra-prepontine cisternal drug infusion system to manage refractory craniofacial pain could provide advantages in terms of minimally invasive, secure, and effective treatment. This application can not only alleviate the suffering of individuals experiencing the prolonged pain but also support the maintenance of quality of life and dignity in their final moments, justifiing its widespread dissemination and standardized adoption in domestic and international professional fields.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017027PMC
http://dx.doi.org/10.11817/j.issn.1672-7347.2024.230597DOI Listing

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Article Synopsis
  • Traditional intrathecal analgesic treatments are insufficient for managing severe craniofacial pain, prompting the development of a new technique for drug delivery via spinal puncture and catheterization in the intra-prepontine cistern.* -
  • A modified Delphi method involving expert consultations led to a consensus on key aspects of the intra-prepontine cisternal drug delivery technique, including principles, indications, and patient management, with over 80% agreement on seven topics.* -
  • This new technique is considered minimally invasive and effective, potentially improving the quality of life for patients with refractory pain, and highlights the need for standardized practices in its application across medical fields.*
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