Selenium is an essential trace element that exists in inorganic forms (selenite and selenates) and organic forms (selenoamino acids, seleno peptides, and selenoproteins). Selenium is known to aid in the function of the immune system for populations where human immunodeficiency virus (HIV) is endemic, as studies suggest that a lack of selenium is associated with a higher risk of mortality among those with HIV. In a recent study conducted in Zambia, adults had a median plasma selenium concentration of 0.27 μmol/L (IQR 0.14-0.43). Concentrations consistent with deficiency (<0.63 μmol/L) were found in 83% of adults. With these results, it can be clearly seen that selenium levels in Southern Africa should be investigated to ensure the good health of both livestock and humans. The recommended selenium dietary requirement of most domesticated livestock is 0.3 mg Se/kg, and in humans above 19 years, anRDA (recommended daily allowance) of 55 mcg Se/per dayisis recommended, but most of the research findings of Southern African countries have recorded low levels. With research findings showing alarming low levels of selenium in soils, humans, and raw feed materials in Southern Africa, further research will be vital in answering questions on how best to improve the selenium status of Southern African soils and plants for livestock and humans to attain sufficient quantities.
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http://dx.doi.org/10.3390/nu16070975 | DOI Listing |
J Med Food
January 2025
Integrative Skin Science and Research, Sacramento, California, USA.
Photoprotective effects of various nutritional components and supplements have been demonstrated in animal and studies. The objective of this systematic review is to assess the photoprotective effects of various dietary supplements. A systematic review of studies assessing dietary supplements on photoprotective outcomes was performed.
View Article and Find Full Text PDFOrg Biomol Chem
January 2025
Department of Pharmacy, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
detection of hypochlorous acid (HOCl) is critical for understanding its complex physiological and pathological roles. Fluorescent probes, known for their sensitivity and selectivity, are the preferred approach for such detections. Anthracene carboxyimide, an analog of naphthalimide, offers extended excitation and emission wavelengths, making it an excellent candidate for developing new fluorescent probes that address the limitations of naphthalimide.
View Article and Find Full Text PDFOrganoselenocyanates have attracted considerable attention in recent years due to their therapeutic potential and versatility in medicinal chemistry. Here, we report on the mechanism of inhibition by 5-phenylcarbamoylpentyl selenocyanide (SelSA-2), an analogue of the well-characterized histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA, a.k.
View Article and Find Full Text PDFInorg Chem
January 2025
State Key Laboratory of Tea Biology and Utilization, Agricultural Photocatalysis Laboratory, School of Materials and Chemistry, Anhui Agricultural University, Hefei 230036, China.
The green and facile biobased functional materials have attracted great attention due to the promising potential to deal with the water pollution of toxic selenium ions that act as a serious threat to human health and the ecological environment. The development of cheap and eco-friendly approaches to remove SeO is of great significance for the safety of drinking water. However, there are some disadvantages in most of the employed methods, such as poor removal capability, high cost, and unsustainability.
View Article and Find Full Text PDFJ Agric Food Chem
January 2025
Key Laboratory of Forage Cultivation, Processing and High Efficient Utilization, Ministry of Agriculture, People's Republic of China, College of Grassland Science, Inner Mongolia Agricultural University, Hohhot 010010, China.
Nanoselenium shows potential trends in improving plant health and food quality. In this study, different concentrations of nanoselenium were sprayed on the leaves of alfalfa. Compared to the control, nanoselenium (100 mg·L) significantly increased SeMet and SeMeCys contents in the roots, stems, and leaves of alfalfa.
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