Background: Isotretinoin is used to treat severe acne, treatment-resistant moderate acne, and acne that leads to scarring or psychological distress. It has many side effects and is also associated with depression, sleep apnea, and sleep disturbances.
Objectives: In this study, we aimed to evaluate the effects of isotretinoin on depression, sleep apnea, and sleep quality.
Methods: A total of 42 patients diagnosed with acne and started isotretinoin treatment were included in the study. In order to compare the effects of isotretinoin, patients were asked to fill out a questionnaire containing the Beck Depression Inventory (BDI), the Berlin Questionnaire (BQ), and the Pittsburg Sleep Quality Index (PSQI) at baseline and third months of treatment.
Results: There was no statistically significant difference in BDI, BQ, and PSQI scores between the 1 and 3 months of treatment ( = .53, = .5, = .35).
Conclusion: This study showed that isotretinoin had no significant effects on depression and sleep quality.
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| http://dx.doi.org/10.1080/15569527.2024.2340435 | DOI Listing |
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