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| http://dx.doi.org/10.4103/aca.aca_1_24 | DOI Listing |
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Evaluation of efficacy of oral ivabradine for attenuation of hemodynamic response to intubation in hypertensive surgical patients: Effect on rate pressure product as an index of myocardial oxygen demand.
J Anaesthesiol Clin Pharmacol
August 2024
Department of Anesthesia, RNT Medical College, Udaipur, Rajasthan, India.
Background And Aims: An exaggerated hemodynamic response to endotracheal intubation is observed in hypertensive patients, and its attenuation proves challenging. The role of oral ivabradine, a unique heart rate-lowering drug with a favorable hemodynamic profile, is not yet studied. The aim of this study was to evaluate the effect of oral ivabradine on the attenuation of hemodynamic response to endotracheal intubation in hypertensive surgical patients assessed by rate pressure product (RPP), which is a very reliable indicator of myocardial oxygen demand.
View Article and Find Full Text PDFEffect of Preoperative Ivabradine on Hemodynamics During Elective Off-pump CABG.
Ann Card Anaesth
April 2024
Department of Cardiothoracic Surgery, G B Pant Institute of Postgraduate Medical Education and Research, J L Nehru Marg, New Delhi, India.
Background: Perioperative myocardial injury is common after major noncardiac surgery and is associated with adverse outcomes. This study investigated the use of ivabradine in patients undergoing urgent surgery for fracture.
Methods And Results: This was a prospective, double-blind, placebo-controlled, randomized clinical trial.
Effect of preoperative ivabradine on hemodynamics during elective off-pump CABG.
Ann Card Anaesth
November 2023
Department of Cardiothoracic Surgery, G B Pant Institute of Postgraduate Medical Education and Research, J L Nehru Marg, New Delhi, India.
Background: Ivabradine is a specific heart rate (HR)-lowering agent which blocks the cardiac pacemaker I channels. It reduces the HR without causing a negative inotropic or lusitropic effect, thus preserving ventricular contractility. The authors hypothesized that its usefulness in lowering HR can be utilized in patients undergoing off-pump coronary artery bypass (OPCAB) surgery.
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Saudi J Anaesth
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Department of Anaesthesia and Intensive Care, Government Medical College and Hospital, Chandigarh, India.
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