AI Article Synopsis
- - Hepatocellular carcinoma (HCC) is a major public health issue with ongoing challenges in treatment, prompting research into innovative solutions like nanodrug delivery systems (NDDS).
- - Engineered cell membrane-coated nanoparticles (ECNPs) combine the benefits of natural cell membranes and synthetic nanoparticles, enhancing drug delivery through targeted therapy and reduced toxicity.
- - This review discusses how ECNPs function and outlines recent advancements in their use for HCC treatment, emphasizing their potential for integrated therapeutic approaches.
Article Abstract
Hepatocellular carcinoma (HCC) has become an important public health problem, and there are still challenges to overcome in clinical treatment. The nanodrug delivery system (NDDS) has developed tremendously in recent years, and many researchers have explored NDDS for the treatment of HCC. Engineered cell membrane-coated nanoparticles (ECNPs) have emerged, combining the unique functions of cell membranes with the engineering versatility of synthetic nanoparticles (NPs) to effectively deliver therapeutic drugs. It is designed to have the capabilities: specific active targeting, immune evasion, prolonging the circulation blood time, controlled drug release delivery, and reducing drugs systematic toxicity. Thus, ECNPs are a promising bionic tool in the treatment of HCC and have operability to achieve combination and integrated therapy. This review focuses on the mechanism and strategy of ECNPs for the treatment of HCC and summarizes its research progress in the treatment of HCC in recent years.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1116/6.0003204 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!