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http://dx.doi.org/10.1016/j.asjsur.2024.03.185 | DOI Listing |
Br J Dermatol
January 2025
Research fellow and General surgery trainee, Royal Marsden Hospital, London, UK.
Melanoma is the fifth most common skin cancer in the UK, accounting for 4% of all new cancer cases, with a predicted 7% increase in incidence between 2014-35. In parallel, since the initial publication of the Melanoma NICE Guidelines in 2015, there has been a paradigm shift in the management of the disease, with the introduction of effective systemic therapies. These innovations have reshaped the management of melanoma throughout the patient journey, and improved clinical outcomes.
View Article and Find Full Text PDFMol Ecol Resour
January 2025
Chair of Urban Water Systems Engineering, Technical University of Munich, Garching, Germany.
Known for its remarkable diversity and ecological importance, the fungal kingdom remains largely unexplored. In fact, the number of unknown and undescribed fungi is predicted to exceed the number of known fungal species by far. Despite efforts to uncover these dark fungal taxa, we still face inherent sampling biases and methodological limitations.
View Article and Find Full Text PDFProg Mater Sci
April 2025
Institute of Biomechanics, Graz University of Technology, Austria.
Aortic dissection continues to be responsible for significant morbidity and mortality, although recent advances in medical data assimilation and in experimental and models have improved our understanding of the initiation and progression of the accumulation of blood within the aortic wall. Hence, there remains a pressing necessity for innovative and enhanced models to more accurately characterize the associated pathological changes. Early on, experimental models were employed to uncover mechanisms in aortic dissection, such as hemodynamic changes and alterations in wall microstructure, and to assess the efficacy of medical implants.
View Article and Find Full Text PDFChemosphere
January 2025
U.S. Environmental Protection Agency, Office of Research and Development, Cincinnati, OH, USA. Electronic address:
Cyanobacteria harmful algal blooms in lakes are primarily driven by nutrient and temperature conditions, yet the interplay of these abiotic factors with microbial community dynamics during bloom events is complex and challenging to unravel. Despite advances through deep sequencing approaches, the underlying transcriptomic changes occurring within blooming and non-blooming taxa remains an actively expanding area of study. In this work, we examined a spring-summer bloom event in Anderson Lake, WA, which has experienced recurring annual blooms dominated by the filamentous, anatoxin-a producing, diazotroph: Dolichospermum sp.
View Article and Find Full Text PDFJ Autoimmun
January 2025
Sorbonne Universités, Department of Internal Medicine and Clinical Immunology, Centre de Référence des Maladies Auto-Immunes Systémiques Rares, Centre de Référence des Maladies Auto-Inflammatoires et de l'Amylose Inflammatoire (CEREMAIA), F-75013, Paris, France; INSERM, UMR_S 959, F-75013, Paris, France; DMU 3ID, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, France.
Background: Non-infectious aortitis encompasses various histological patterns, but their specific cardiovascular outcomes remain unclear.
Objective: To evaluate the mortality associated with non-infectious surgical thoracic aortitis.
Methods: This retrospective multicenter study included patients who underwent thoracic aortic surgery and had histological evidence of aortitis.
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