AI Article Synopsis

  • Gene regulatory networks (GRNs) are complicated systems that show how genes and regulators work together to control gene expression.!
  • Studying GRNs is important for understanding how insects develop and adapt because their gene regulation is more complex than in other organisms.!
  • This review talks about different mathematical models used to study GRNs in insects, compares them, and looks at how well they work in real-life situations.!

Article Abstract

Gene regulatory network (GRN) comprises complicated yet intertwined gene-regulator relationships. Understanding the GRN dynamics will unravel the complexity behind the observed gene expressions. Insect gene regulation is often complicated due to their complex life cycles and diverse ecological adaptations. The main interest of this review is to have an update on the current mathematical modelling methods of GRNs to explain insect science. Several popular GRN architecture models are discussed, together with examples of applications in insect science. In the last part of this review, each model is compared from different aspects, including network scalability, computation complexity, robustness to noise and biological relevancy.

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http://dx.doi.org/10.1016/j.pbiomolbio.2024.04.002DOI Listing

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