Introduction: Giant cell lesions of orofacial region although rare in presentation, have diagnostic and treatment challenges due to overlapping clinical, radiological, and histopathological signs.
Background: We happened to come across a case, which presented to us with an aggressive jaw lesion of nonodontogenic origin, mimicking a malignancy and putting us in a conundrum with regard to work up and treatment. The sequential work up not only helped us reach a definitive diagnosis but also led us the draw algorithms for diagnosis of Giant cell lesions and management of Central giant cell granuloma.
Conclusion: Meticulous planning along with molecular studies helps in better delineating one giant cell lesion from other.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11001811 | PMC |
| http://dx.doi.org/10.1007/s12663-023-02004-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dynamic flow control through active matter programming language.
Nat Mater
January 2025
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Cells use 'active' energy-consuming motor and filament protein networks to control micrometre-scale transport and fluid flows. Biological active materials could be used in dynamically programmable devices that achieve spatial and temporal resolution that exceeds current microfluidic technologies. However, reconstituted motor-microtubule systems generate chaotic flows and cannot be directly harnessed for engineering applications.
View Article and Find Full Text PDFIs Bilateral Temporal Artery Biopsy More Effective than Unilateral to Diagnose Giant Cell Arteritis?
Laryngoscope
January 2025
Department of Otolaryngology/Head & Neck Surgery, University of California San Diego, San Diego, California, USA.
SARS-CoV-2 S-protein expression drives syncytia formation in endothelial cells.
Sci Rep
January 2025
Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
SARS-CoV-2 is a viral infection, best studied in the context of epithelial cell infection. Epithelial cells, when infected with SARS-CoV-2 express the viral S-protein, which causes host cells to fuse together into large multi-nucleated cells known as syncytia. Because SARS-CoV-2 infections also frequently present with cardiovascular phenotypes, we sought to understand if S-protein expression would also result in syncytia formation in endothelial cells.
View Article and Find Full Text PDFMechanics of cell sheets: plectin as an integrator of cytoskeletal networks.
Open Biol
January 2025
Laboratory of Integrative Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.
Epithelia are multicellular sheets that form barriers defining the internal and external environments. The constant stresses acting at this interface require that epithelial sheets are mechanically robust and provide a selective barrier to the hostile exterior. These properties are mediated by cellular junctions which are physically linked with heavily crosslinked cytoskeletal networks.
View Article and Find Full Text PDFChromosome-scale genome assembly reveals how repeat elements shape non-coding RNA landscapes active during newt limb regeneration.
Cell Genom
January 2025
Department of Cell and Molecular Biology, Karolinska Institute, 171 65 Stockholm, Sweden. Electronic address:
Newts have large genomes harboring many repeat elements. How these elements shape the genome and relate to newts' unique regeneration ability remains unknown. We present here the chromosome-scale assembly of the 20.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!