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Development of a Mobile Laser Measurement System for Subway Tunnel Deformation Detection.
Sensors (Basel)
January 2025
School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221000, China.
In recent years, mobile laser measurement systems have markedly enhanced the capabilities of deformation detection and defect identification within metro tunnels, attributed to their superior efficiency, precision, and versatility. Nevertheless, challenges persist, including substantial equipment costs, inadequate after-sales support, technological barriers, and limitations in customization. This paper develops a mobile laser measurement system that has been specifically developed for the purpose of detecting deformation in metro tunnels.
View Article and Find Full Text PDFReducing Hospital Readmissions in Chronic Obstructive Pulmonary Disease Patients: Current Treatments and Preventive Strategies.
Medicina (Kaunas)
January 2025
Respiratory Medicine Unit, Department of Medicine, University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, 37134 Verona, Italy.
COPD is one of the leading causes of death worldwide, so it represents a significant public health challenge. Over the years, new effective therapies have been proposed. However, the burden of COPD is still conditioned by frequent acute events defined as exacerbations (exacerbation of COPD-ECOPD), which have a significant impact not only on the patient's quality of life but also on the progression of the disease, morbidity, and mortality.
View Article and Find Full Text PDFCombined biochemical profiling and DNA sequencing in the expanded newborn screening for inherited metabolic diseases: the experience in an Italian reference center.
Orphanet J Rare Dis
January 2025
Department of Translational Medicine, University of Naples "Federico II", Naples, Italy.
Background: Newborn screening (NBS) programs have significantly improved the health and outcomes of patients with inherited metabolic disorders (IMDs). Methods based on liquid chromatography/mass spectrometry (LC-MS/MS) analysis are viewed worldwide as the gold standard procedure for the expanded NBS programs for these disorders. Advanced molecular technologies point to genomic sequencing as an alternative and feasible strategy for the screening of genetic diseases, including IMDs.
View Article and Find Full Text PDFCorrection: Preventing preterm birth with progesterone: costs and effects of screening low risk women with a singleton pregnancy for short cervical length, the Triple P study.
BMC Pregnancy Childbirth
January 2025
Department of Obstetrics and Gynaecology, Leiden University Medical Centre, Leiden, the Netherlands.
Digital Melting Curve Analysis for Multiplex Quantification of Nucleic Acids on Droplet Digital PCR.
Biosensors (Basel)
January 2025
State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Si Pai Lou 2, Nanjing 210096, China.
We present a cost-effective and simple multiplex nucleic acid quantification method using droplet digital PCR (ddPCR) with digital melting curve analysis (MCA). This approach eliminates the need for complex fluorescent probe design, reducing both costs and dependence on fluorescence channels. We developed a convolutional neighborhood search algorithm to correct droplet displacement during heating, ensuring precise tracking and accurate extraction of melting curves.
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