Streamlining mouse genome editing by integrating AAV repair template delivery and CRISPR-Cas electroporation.

Lab Anim (NY)

Genome Editing and Mouse Models, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK.

Published: May 2024

Recent genome editing techniques have substantially simplified the generation of genetically modified mice. A new study combines adeno-associated viruses (AAV) and electroporation to generate a robust pipeline to deliver CRISPR-Cas reagents into mouse embryos.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11068566PMC
http://dx.doi.org/10.1038/s41684-024-01363-wDOI Listing

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