Activation of the peripheral immune system contributes to stress-related neuropsychiatric symptoms. Recently in Nature, Cathomas et al. demonstrate that stress-induced social avoidance is mediated by monocyte-derived MMP8 that remodels the extracellular space of the nucleus accumbens.
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New insights into roles of IL-7R gene as a diagnostic biomarker for post-stroke depression.
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View Article and Find Full Text PDFThe Anti-Inflammatory Roles of Vitamin D for Improving Human Health.
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Vitamin D receptors (VDRs) are present in almost all cells of the immune system, including B cells, T cells, NK (Natural Killer) cells, dendritic cells, and monocytes, as well as the epithelial cells of many organs such as the intestine, pancreas, prostate, lungs, and cardiomyocytes. In addition, some immune cells, including dendritic cells, macrophages, and B and T cells, can synthesize calcitriol by expressing 1α-hydroxylase. Upon binding to VDRs, vitamin D (Vit D) regulates the expression of genes involved in immune responses, including those encoding for cytokines.
View Article and Find Full Text PDFRetrospective evaluation of novel serum inflammatory biomarkers in first-episode psychiatric disorders: diagnostic potential and immune dysregulation.
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Department of Clinical Laboratory, The Mental Health Center of Kunming Medical University, Kunming, China.
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Association between psychiatric symptoms with multiple peripheral blood sample test: a 10-year retrospective study.
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West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, China.
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View Article and Find Full Text PDFAssociation of Sympathovagal Imbalance with Increased Inflammation and Impaired Adaptive Immunity in Bladder Cancer Patients.
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Institute of Immunology, Faculty of Medicine, Comenius University in Bratislava, Odborarske namestie 14, 811 08 Bratislava, Slovakia.
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