Comparison of Different Betadine and Saline Combinations on Microorganisms: An Original Research.

J Pharm Bioallied Sci

Department of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India.

Published: February 2024

Introduction: Pathogenic bacteria in the oral cavity or a physiological microbiome imbalance can cause or maintain disease. Thus, this work examined a novel betadine-saline combination for antibacterial and antifungal activities.

Materials And Methods: This study was . Betadine, saline, and their mixtures were tested for , (gram-positive), , , and (gram-negative). Pour plate and disc diffusion methods were used to test CFUs, DZI, and RZI for various agent combinations.

Results: For , Betadine 90% + saline 10% had the greatest DZI and RZI at 24 and 12 mm, respectively. For , Betadine 50% + saline 50% had the highest at 16 and 8 mm. Betadine 60% + saline 40% had 14 mm RZI and the highest antifungal activity.

Conclusion: The novel betadine-saline antibacterial and antifungal combination performed well. research should confirm the existing findings.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11000963PMC
http://dx.doi.org/10.4103/jpbs.jpbs_470_23DOI Listing

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