AI Article Synopsis

  • Retinoblastoma is the most common eye cancer in children, and challenges in diagnosis and treatment remain, especially in low- and middle-income countries.
  • A systematic review identified 21 studies focused on strategies like surveillance, genetic counseling, education, public assistance, and international partnerships that can improve diagnosis and treatment access.
  • Proposed initiatives from the review aim to enhance clinical outcomes for retinoblastoma patients, emphasizing the need for systematic implementation of these strategies.

Article Abstract

Retinoblastoma, the most common intraocular tumor in childhood, still faces challenges in diagnosis and treatment, particularly in low- and middle-income countries. Identifying strategies to improve the time to diagnosis and access to treatment is crucial to enhance survival rates and preserve ocular health. We conducted a systematic review to identify interventions that have demonstrated potential in addressing these challenges. We performed a comprehensive search across databases until March 2023. Out of the studies reviewed, 21 met the inclusion criteria and were categorized into five main areas: surveillance strategies, genetic counseling, education, public assistance, and international partnership. Despite the obstacles faced, the initiatives identified in this review present acts toward improving the time to diagnosis and access to treatment for retinoblastoma. Based on the extracted data, we propose a comprehensive chain of initiatives. We firmly believe that implementing this chain of initiatives can lead to improved clinical outcomes for retinoblastoma patients.

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http://dx.doi.org/10.1002/pbc.30987DOI Listing

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