Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Piezo1 Enhances Macrophage Phagocytosis and Pyrin Activation to Ameliorate Fungal Keratitis.
Invest Ophthalmol Vis Sci
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China.
Purpose: Fungal keratitis (FK) remains a treatment challenge, necessitating new therapeutic targets. Piezo1, a mechanosensitive ion channel, regulates calcium signaling and immune cell function. This study investigates its role in macrophage-mediated antifungal responses in FK.
View Article and Find Full Text PDF[The impact of mitochondrial transfer on leukemia progression].
Sheng Li Xue Bao
December 2024
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
The objective of the present study was to investigate the role and mechanism of bone marrow microenvironmental cells in regulating the mitochondrial mass of leukemia cells, and to uncover the mechanism of leukemia progression at the metabolic level. A mouse model of acute myeloid leukemia (AML) induced by the overexpression of the MLL-AF9 (MA9) fusion protein was established, and the bone marrow cells of AML mice were transplanted into mitochondrial fluorescence reporter mice expressing the Dendra2 protein (mito-Dendra2 mice). The proportion of Dendra2 cells in bone marrow leukemia cells at different stages of AML was quantified by flow cytometry.
View Article and Find Full Text PDFMultifunctional Hydrogel with Photothermal ROS Scavenging and Antibacterial Activity Accelerates Diabetic Wound Healing.
Adv Healthc Mater
January 2025
Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Poor diabetic wound healing poses a critical threat to human health. Excessive oxidative stress and increased susceptibility to bacterial infection are key issues that impede diabetic wound healing. Cerium oxide nanoparticles (CeO NPs) have attracted increasing attention because of their unique antioxidant and antimicrobial properties.
View Article and Find Full Text PDF[Generation and Evaluation of Human Umbilical Cord Derived Mesenchymal Stem Cells with Antioxidant Capacity].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2024
Life Science School of Hebei University, Baoding 071000, Hebei Province, China.
Article Synopsis
- The study aimed to prepare antioxidant-capable mesenchymal stem cells (AO-MSC) from human umbilical cords and assess their biological properties.
- The AO-MSC were isolated using a method that involved allowing tissue debris to adhere to the culture surface, while control cells were obtained through traditional collagenase digestion.
- Results demonstrated that AO-MSC displayed higher levels of antioxidant substances and good self-renewal ability, but had a weaker capacity for adipogenic and osteogenic differentiation compared to conventional MSC.
Encapsulation, Shelf Life, and Virulence of sp. Against .
J Fungi (Basel)
November 2024
Department of Entomology and Acarology, "Luiz de Queiróz" College of Agriculture, University of São Paulo (ESALQ/USP), Piracicaba 13418-900, Brazil.
is a genus of entomophthoralean fungi often associated with insect epizootics, particularly in phytophagous hemipterans. Encapsulation has become a promising strategy for improving the shelf life and sporulation of these fungi post-application. This study aims to (i) compare the virulence of the submerged propagules and primary conidia of sp.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!