Elucidating the intricacies of the HS signaling pathway in gasotransmitters: Highlighting the regulation of plant thiocyanate detoxification pathways.

In recent decades, there has been increasing interest in elucidating the role of sulfur-containing compounds in plant metabolism, particularly emphasizing their function as signaling molecules. Among these, thiocyanate (SCN), a compound imbued with sulfur and nitrogen, has emerged as a significant environmental contaminant frequently detected in irrigation water. This compound is known for its potential to adversely impact plant growth and agricultural yield. Although adopting exogenous SCN as a nitrogen source in plant cells has been the subject of thorough investigation, the fate of sulfur resulting from the assimilation of exogenous SCN has not been fully explored. There is burgeoning curiosity in probing the fate of SCN within plant systems, especially considering the possible generation of the gaseous signaling molecule, hydrogen sulfide (HS) during the metabolism of SCN. Notably, the endogenous synthesis of HS occurs predominantly within chloroplasts, the cytosol, and mitochondria. In contrast, the production of HS following the assimilation of exogenous SCN is explicitly confined to chloroplasts and mitochondria. This phenomenon indicates complex interplay and communication among various subcellular organelles, influencing signal transduction and other vital physiological processes. This review, augmented by a small-scale experimental study, endeavors to provide insights into the functional characteristics of HS signaling in plants subjected to SCN-stress. Furthermore, a comparative analysis of the occurrence and trajectory of endogenous HS and HS derived from SCN-assimilation within plant organisms was performed, providing a focused lens for a comprehensive examination of the multifaceted roles of HS in rice plants. By delving into these dimensions, our objective is to enhance the understanding of the regulatory mechanisms employed by the gasotransmitter HS in plant adaptations and responses to SCN-stress, yielding invaluable insights into strategies for plant resilience and adaptive capabilities.