AI Article Synopsis
- COVID-19, caused by the SARS-CoV-2 virus first identified in Wuhan in December 2019, has developed into the largest pandemic in a century, primarily affecting the lungs but also impacting multiple organs.
- Evidence indicates that COVID-19 can lead to complications in the heart, brain, kidneys, and gastrointestinal system, highlighting its systemic nature and variances in symptom presentation and severity.
- This review aims to explore the non-pulmonary effects of COVID-19, emphasizing the underlying mechanisms and clinical manifestations associated with these complications.
Article Abstract
First described in December 2019 in Wuhan (China), COVID-19 disease rapidly spread worldwide, constituting the biggest pandemic in the last 100 years. Even if SARS-CoV-2, the agent responsible for COVID-19, is mainly associated with pulmonary injury, evidence is growing that this virus can affect many organs, including the heart and vascular endothelial cells, and cause haemostasis, CNS, and kidney and gastrointestinal tract abnormalities that can impact in the disease course and prognosis. In fact, COVID-19 may affect almost all the organs. Hence, SARS-CoV-2 is essentially a systemic infection that can present a large number of clinical manifestations, and it is variable in distribution and severity, which means it is potentially life-threatening. The goal of this comprehensive review paper in the series is to give an overview of non-pulmonary involvement in COVID-19, with a special focus on underlying pathophysiological mechanisms and clinical presentation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10932259 | PMC |
| http://dx.doi.org/10.3390/jcm13051397 | DOI Listing |
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