AI Article Synopsis
- This study examined how different technical performance parameters of embryo transfer (ET) impact IVF outcomes using data from 1417 ET procedures.
- It found that individual ET parameters generally did not show significant effects on clinical outcomes, while factors like the number and quality of embryos, along with maternal age, were significant predictors.
- Ultimately, the research concluded that tracking detailed ET parameters does not provide added value for predicting IVF success, reinforcing the importance of embryo quality and maternal factors.
Article Abstract
Background: this study aims to assess the effect of embryo transfer (ET) performance parameters of a technical nature on IVF outcome.
Methods: A total of 1417 ETs from a single IVF center were included in this prospective observational study. The parameters investigated were as follows: the presence of cervical mucus post catheter withdrawal, the presence of blood, catheter reload, the employment of a tenaculum and stylet, catheter resistance as experienced by the physician and patient discomfort.
Results: When ET performance parameters were associated with clinical outcomes on a singular level, none of the ET parameters presented with any statistical significance. The evaluation of covariates indicated that the number and the quality of transferred embryos, as well as maternal age, exerted a statistically significant effect on clinical outcomes. In a multivariate analysis, only the presence of mucus along with significant catheter resistance presented with statistical significance; however, when adjusting for covariates, this combination showed no statistically significant effect on clinical outcomes.
Conclusions: the results indicate that the time-consuming process of recording and analyzing ET performance parameters fails to offer any additional value in predicting the cycle's outcome, while factors like embryo quality and number, as well as maternal age, seem to be the sole robust predictive factors of an IVF cycle.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10931750 | PMC |
| http://dx.doi.org/10.3390/jcm13051312 | DOI Listing |
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