Consent for High-Kidney Donor Profile Index Kidneys: The Responsibility of Transplant Centers to Get it Right.

J Am Soc Nephrol

Division of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, California.

Published: May 2024

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149028PMC
http://dx.doi.org/10.1681/ASN.0000000000000351DOI Listing

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Article Synopsis
  • A national study found that 41% of kidney transplant candidates consented to receive high-Kidney Donor Profile Index (KDPI) donor offers, showing significant variation based on individual characteristics and transplant centers.
  • Consent for high-KDPI kidneys correlated with a 15% increase in adjusted rates of deceased donor transplants, suggesting that those who consent are more likely to receive transplants.
  • Factors influencing consent included age, race (Black or Hispanic), higher body mass index, and certain health conditions, with a notable variation in consent rates across different transplant centers.
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Anti-aging protein klotho was associated with vitamin B12 concentration in adults.

Medicine (Baltimore)

October 2022

Department of Preventive Medicine, College of Medicine, Seoul National University, Seoul, Republic of Korea.

Previous studies have reported that serum klotho and vitamin B12 levels are valuable aging-related markers. However, studies supporting the association between serum klotho and vitamin B12 levels are lacking. We investigated the association between serum klotho and vitamin B12 concentrations in adults in the United States.

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