AI Article Synopsis

  • Physical activity (PA) is important for combatting obesity, but the best patterns for effectiveness are still unclear, particularly in relation to a novel obesity indicator called the cardiometabolic index (CMI).
  • A study analyzing data from 16,442 U.S. adults found that only those who were regularly active showed a significant reduction in CMI, while those categorized as "weekend warriors" did not see similar benefits.
  • The analysis also suggested that the relationship between PA and CMI was stronger in younger and older adults, those with higher education, and current drinkers, indicating that engaging in over 330 minutes of PA weekly could lead to better CMI outcomes.

Article Abstract

Background: Physical activity (PA) is widely recommended for preventing and combating obesity, but the most effective PA pattern for treating obesity remains unclear. Cardiometabolic index (CMI), derived from waist height ratio and triglycerides to high-density lipoprotein-cholesterol ratio, is a novel indicator for evaluating obesity. However, the relationship between different PA patterns and CMI remains unelucidated.

Objective: This study aimed to explore the association between different PA patterns and CMI in U.S. adults.

Methods: Participants with complete information in CMI, PA patterns, and other covariates in the National Health and Nutrition Examination Survey database (2007-2016) were included in this study. Multivariate linear regression models were utilized to explore the relationship between PA patterns and CMI. Moreover, stratified analyses, interaction tests and restricted cubic spline (RCS) regression analysis were used to investigate the stability and nonlinearity of the association, respectively.

Results: A total of 16,442 adults were included in this study. After adjusting for all potential covariates, only the regularly active group was significantly associated with CMI reduction (β = -0.13, 95% CI: 0.19 to -0.07, P < 0.0001), while the weekend warriors group did not achieve equivalent CMI reduction (β = -0.09, 95% CI: 0.32 to 0.14, P = 0.4204). Subgroup analyses and interaction tests revealed that the CMI-PA association was more pronounced in the subgroup with age≤45 or >60, with higher education level, and who are current drinkers. Furthermore, RCS analysis indicated that total PA in a week was significantly, nonlinearly associated with CMI in non-inactive adults, and that a total of PA more than 330 min can reap favorable CMI reduction.

Conclusion: Being regularly active is associated with significant CMI reduction, while being weekend warriors and insufficiently active do not achieve equivalent benefits. For non-inactive individuals, engaging in PA for more than 330 min weekly helps to reduce CMI effectively.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10998206PMC
http://dx.doi.org/10.1016/j.heliyon.2024.e28792DOI Listing

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