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Dysphagia in multiple sclerosis: pathophysiology, assessment, and management-an overview.
Front Neurol
December 2024
Unit of Neurology, IRCCS Neuromed, Pozzilli, Italy.
Dysphagia is a frequent and life-threatening complication of multiple sclerosis (MS). Swallowing disturbances may be present at all stages of MS, although their prevalence increases with age, with disease duration, and in progressive phenotypes. The pathophysiology of dysphagia in MS is likely due to a combination of factors, including the involvement of corticobulbar tracts, the cerebellum, and the brainstem.
View Article and Find Full Text PDFThe time-course changes in postural control variability between neck pain and asymptomatic dental students.
Sci Rep
December 2024
Neuromuscular Research Lab, Interdisciplinary Centre for the study of Human Performance (CIPER), Faculty of Human Kinetics, University of Lisbon, 1499-002, Oeiras, Portugal.
Changes in postural control associated with clinical practice or specific conditions such as the presence of neck pain remain unexplored in dental students. Therefore, this study aimed to explore the time-course changes in postural control complexity among dental students enrolled in clinical practice, comparing those with and without neck pain. We used an online Nordic Musculoskeletal Questionnaire for group allocation and center of pressure (CoP) oscillations with a tri-axial Bertec force plate.
View Article and Find Full Text PDFEnhanced Osseointegration of Titanium Alloy Bone Implants Coated With Carob-calcium Hydroxide Nanoparticles: A Comparative Study.
J Craniofac Surg
December 2024
Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University.
Objectives: This study aimed to evaluate the osseointegration properties of titanium bone implants coated with carob-mediated calcium hydroxide nanoparticles biomechanically, radiographically, and histologically on rabbit tibias.
Material And Methods: Forty coated and forty uncoated titanium alloy bone implants were inserted into 20 New Zealand rabbits; each tibia received 2 implants. The rabbits were sacrificed after 4 or 8 weeks, and samples were retrieved for biomechanical evaluation through removal torque test to assess the bond between implant and bone, radiographic evaluation through microcomputed tomography analysis to compare the bone-to-implant contact percentage and bone volume of the peri-implant area, scanning electron microscopic and histologic evaluation through hematoxylin and eosin stain.
A Novel Dual Cross-linking Reagent for Dentin Bonding Interface Stability.
J Dent Res
December 2024
State Key Lab of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
The cross-linking reagent has been proposed as a means of modifying dentin collagen, inhibiting matrix metalloproteinase activities, and enhancing bond durability during dentin bonding procedures. This study aimed to synthesize an operation-friendly dual cross-linking reagent-3-(4-formyphenoxy)-2-hydroxypropyl methacrylate (FPA)-to assess its ability to cross-link dentin collagen and reduce enzymatic activity at the bonding interface. Cytotoxicity was evaluated by a cell counting kit-8 test and calcein AM/propidium iodide assay.
View Article and Find Full Text PDFStructural and functional connectomics of the olfactory system in Parkinson's disease: a systematic review.
Parkinsonism Relat Disord
December 2024
Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy. Electronic address:
Olfactory dysfunction, affecting 75-90 % of Parkinson's disease (PD) patients, holds significant predictive value for PD development. Advanced imaging techniques, such as diffusion MRI (dMRI) and functional MRI (fMRI), offer insights into structural and functional changes within olfactory pathways. This review summarizes a decade of research on MRI-based connectivity of the olfactory system in PD, focusing on structural and functional alterations in olfactory brain areas and their links to early olfactory processing changes.
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