We assessed acceptability of nonoral HIV pre-exposure prophylaxis (PrEP) formulations among transgender women (TW) engaged in street-based sex work in Baltimore, Maryland. In a -means cluster analysis, TW (=36) were partitioned into groups characterized by high interest in long-acting injectable PrEP only (, 36%), high interest in injectables and subdermal implants (, 36%), and low interest across PrEP formulations (, 28%). TW's interest in novel PrEP agents varied widely across formulations (range: 22-66%) and clustered around numerous relational, occupational, and structural factors, highlighting the importance of availing multiple PrEP formulations for this impacted population.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10998007PMC
http://dx.doi.org/10.1089/trgh.2022.0057DOI Listing

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