We assessed acceptability of nonoral HIV pre-exposure prophylaxis (PrEP) formulations among transgender women (TW) engaged in street-based sex work in Baltimore, Maryland. In a -means cluster analysis, TW (=36) were partitioned into groups characterized by high interest in long-acting injectable PrEP only (, 36%), high interest in injectables and subdermal implants (, 36%), and low interest across PrEP formulations (, 28%). TW's interest in novel PrEP agents varied widely across formulations (range: 22-66%) and clustered around numerous relational, occupational, and structural factors, highlighting the importance of availing multiple PrEP formulations for this impacted population.
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http://dx.doi.org/10.1089/trgh.2022.0057 | DOI Listing |
AIDS Behav
January 2025
Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Although people who inject drugs (PWID) are at high risk of acquiring HIV, knowledge and uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among this population remain low due to numerous psychosocial and structural barriers. Multiple implementation strategies have been proposed to address this gap, notably providing long-acting injectable (LAI) formulations of PrEP and offering PrEP at syringe services programs (SSPs). This qualitative study explores the acceptability and feasibility of offering LAI-PrEP for PWID at risk for HIV at Florida's first legal SSP.
View Article and Find Full Text PDFBMC Infect Dis
January 2025
Department of Global Health, University of Washington, Seattle, USA.
Background: Increased risk of HIV acquisition during pregnancy and lactation among women is evident, necessitating their inclusion in the evaluation of new HIV prevention interventions. Pregnant and postpartum women specifically face challenges with oral PrEP associated with stigma, and the burden of using other tablets. Long-acting products may address challenges related to oral PrEP, however, there is limited data on product-specific preferences and acceptability among pregnant and lactating women.
View Article and Find Full Text PDFDisaster Med Public Health Prep
January 2025
Department of Neurosurgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai200120, China.
Objectives: Compared with first-tier cities in China that are of abundant funds and resources like legions of high-level hospitals, the degree of nurses' disaster nursing preparedness in non-first-tier cities (inland) is relatively lower. For example, nurses' knowledge reserve of specific disasters is not comprehensive enough. And nurses are diffident when it comes to the skills of handling disaster rescue.
View Article and Find Full Text PDFDisaster Med Public Health Prep
January 2025
Auckland University of Technology (AUT), Department of Computer Science and Software Engineering, Auckland, New Zealand.
Objectives: This systematic literature review explores the applications of social network platforms for disaster health care management and resiliency and investigates their potential to enhance decision-making and policy formulation for public health authorities during such events.
Methods: A comprehensive search across academic databases yielded 90 relevant studies. Utilizing qualitative and thematic analysis, the study identified the primary applications of social network data analytics during disasters, organizing them into 5 key themes: communication, information extraction, disaster Management, Situational Awareness, and Location Identification.
Int J Pharm
December 2024
Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH 45229, USA. Electronic address:
Conventional drug formulations release active pharmaceutical ingredients (APIs) immediately after administration, while long-acting (LA) drug products are designed for prolonged therapeutic effects, thereby reducing administration frequency and improving patient compliance. The development of LA therapeutics for chronic disease treatment has significantly helped patients adhere to their regimens, reducing the need for daily doses and easing the burden on healthcare systems. Advances in treatment have transformed Human Immunodeficiency Virus (HIV) into a manageable chronic disease, and efforts are underway to eliminate HIV in the future.
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