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Cost-effectiveness analysis of pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in the Chinese healthcare system.
Front Pharmacol
January 2025
Department of Oncology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region, Guilin, China.
Objective: The combination of pembrolizumab and chemotherapy has demonstrated notable clinical advantages in improving overall survival than chemotherapy alone for patients with untreated advanced pleural mesothelioma. The purpose of this study was to assess its cost-effectiveness.
Materials And Methods: A Markov state-transition model was constructed using data from the IND227 phase 3 randomized clinical trial.
Rare confounder: benign multicystic peritoneal mesothelioma in a patient with mucinous colon adenocarcinoma.
J Surg Case Rep
September 2024
Division of Gastrointestinal Surgery, University of Florida College of Medicine, 1600 SW Archer Road, Rm 6165, PO Box 100109, Gainesville, FL 32601, United States.
Benign multicystic peritoneal mesothelioma (BMPM) is a rare condition, in which patients have multiple cystic lesions of the peritoneum. BMPM can mimic mucinous carcinomatosis and can thus create a diagnostic dilemma. We present the case of a 76-year-old woman who was referred for management of ascending colon adenocarcinoma and was noted to have several nonspecific cystic lesions in the abdomen and pelvis on preoperative computed tomography and diagnostic laparoscopy.
View Article and Find Full Text PDFRegarding NF2 (Merlin) Status in Mesothelioma of Uncertain Malignant Potential (MUMP) or Complex Mesothelial Tumor of the Tunica Vaginalis.
Am J Surg Pathol
September 2024
Department of Pathology, Johns Hopkins University School of Medicine Baltimore, MD.
Current clinical practices of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Innov Surg Sci
March 2024
Department of General and Visceral Surgery, Hospital Barmherzige Brüder, Regensburg, Germany.
Treatment of peritoneal surface malignancies makes physicians face demanding and new-fangled problems, as there are many uncertain aspects considering the outcomes of affected patients' prognoses. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are associated with favorable long-term outcomes in carefully selected patients with peritoneal metastases (PM). We aim to summarize the current results about the initial malignancies and their peritoneal spreads.
View Article and Find Full Text PDFValidity of Pleuroscopy in Evaluating Pleural Effusions of Uncertain Etiology at the Cardiothoracic Unit of Minia University Hospital, Egypt.
Cureus
April 2024
Department of Chest Diseases, Minia University, Minia, EGY.
Introduction: Pleural effusion is a medical condition where an excessive amount of fluid accumulates in the pleural space. This can be caused by inflammation or malignant growth in the body. Doctors use medical thoracoscopy for both diagnostic and therapeutic purposes.
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