Chronic rhinosinusitis possibly associated with decreased lung function in chronic cough patients.

Braz J Otorhinolaryngol

Okayama University Academic Field of Medicine, Dentistry and Pharmaceutical Sciences, Department of Otolaryngology-Head and Neck Surgery, Okayama, Japan.

Published: July 2024

AI Article Synopsis

  • This study aims to explore lung function in patients suffering from Chronic Rhinosinusitis (CRS) who also experience Chronic Cough (CC).
  • It involved analyzing 109 CRS patients with CC and comparing their lung function metrics to those of normal control subjects, revealing significantly lower lung function in the CRS group.
  • The findings suggest that CRS patients with CC need thorough lung function evaluations, and a team approach with various specialists, including pulmonologists, is essential for effective management.

Article Abstract

Objectives: The purpose of this study is to investigate the lung function in Chronic Rhinosinusitis (CRS) patients with Chronic Cough (CC).

Methods: A total of 1413 CC patients were retrospectively screened and 109 CRS patients with CC were enrolled. Lung function, Lund-Mackay Computed Tomography (CT) score, smoking status, peripheral blood eosinophil count, and immunoglobulin E concentration in serum samples, and Sino-Nasal Outcome Test were examined. Normal control subjects are also recruited.

Results: The Forced Expiratory Volume in 1 second (FEV), Percent Predicted FEV, and FEV/Forced Vital Capacity (FVC) ratio in the patients were significantly low as compared with the control subjects. The FEV/FVC ratio was negatively correlated with the Lund-Mackay CT scores of the patients with a high CT score.

Conclusions: The CRS patients with CC should be investigated with lung function. In addition, the multidisciplinary evaluation including a pulmonologist is needed to manage the CRS patients with CC.

Level Of Evidence: Level 4.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11004496PMC
http://dx.doi.org/10.1016/j.bjorl.2024.101424DOI Listing

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