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http://dx.doi.org/10.3389/fendo.2024.1387889 | DOI Listing |
J Alzheimers Dis
January 2025
Department of Neurology, The Seventh Medical Center of PLA General Hospital, Beijing, China.
Disruption of circadian rest-activity rhythm (RAR) has been found in many neurological disorders. In this study, actigraphic data were collected and analyzed to identify the RAR pattern in the elderly with cerebral small vessel disease. 115 cerebral small vessel disease (CSVD) cases were recruited.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
January 2025
AP-HP.Nord Université Paris Cité, Service d'Endocrinologie et Diabétologie Pédiatrique, Centre de Référence Maladies Endocriniennes Rares de la Croissance et du Développement, Hôpital Universitaire Robert-Debré, Paris 75019, France.
Front Oncol
December 2024
Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Introduction: Lung cancer is the first cause of cancer death in the world, due to a delayed diagnosis and the absence of efficacy therapies. KRAS mutation occurs in 25% of all lung cancers and the concomitant mutations in LKB1 determine aggressive subtypes of these tumors. The improvement of therapeutical options for KRASG12C mutations has increased the possibility of treating these tumors, but resistance to these therapies has emerged.
View Article and Find Full Text PDFPsychiatry Investig
December 2024
Department of Psychiatry, Korea University College of Medicine, Seoul, Republic of Korea.
Front Med (Lausanne)
December 2024
Department of Family Medicine, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
The role of chronic stress in the development of chronic diseases, especially multimorbidity, through the pathways of increasing allostatic load, and finally, allostatic overload (the state when a compensatory mechanism is likely to fail) is being emphasized. However, allostatic load is a dynamic measure that changes depending on sex, gender, age, level and type of stress, experience of a stressful situation, and coping behaviors. Many other factors such as race, ethnicity, working environment, lifestyle, and circadian rhythm of sleep are also important.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!