Objective: The objective of this study was to produce a cross-cultural adaptation in Italian of the Agitated Behavior Scale (ABS), originally developed in English, as the first of two stages that also include cross-cultural validation and allow a clinical scale to be used in the proper setting such as rehabilitation units.
Methods: In order to adapt the ABS scale to a different cultural environment, five consecutive steps were performed: (1) forward translations (n = 8), (2) synthesis of the 8 forward translations to obtain a first shared italian version (ABS_I_trial), (3) back translations (n = 3), (4) creation of an expert committee to evaluate forward and back translations and finally (5) the cognitive debriefing.
Results: After the five steps, including forward translations and back translations, the process of committee verification and judgement and the evaluative step of cognitive debriefing, high comprehensibility of all items was found, resulting in an Italian translation version of ABS suitable for application in a clinical setting.
Conclusion: ABS translation was produced by means of a standardized procedure aimed at minimizing cross-cultural gaps. The expert committee evaluated the version produced as highly understandable in Italian. Further steps, such as the subsequent validation of its psychometric properties, are needed to employ this translation in a clinical setting.
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http://dx.doi.org/10.2340/jrm.v56.11663 | DOI Listing |
Res Nurs Health
January 2025
School of Nursing, Hubei University of Medicine, Shiyan, Hubei, China.
The management of heart failure in patients presents a significant challenge to global public health, marked by an increase in unaddressed needs due to the extended deterioration of health. It is crucial to conduct comprehensive assessments of patients with heart failure, thereby providing personalized care. The purpose of this study was to translate, adapt, and validate the Needs Assessment Questionnaire for people with heart failure in Mainland China and to evaluate its reliability and validity within a population of people with heart failure.
View Article and Find Full Text PDFComput Struct Biotechnol J
December 2024
Centre for the Technologies of Gene and Cell Therapy, National Institute of Chemistry, Hajdrihova 19, SI1000 Ljubljana, Slovenia.
The emerging field of precision medicine relies on scientific breakthroughs to understand disease mechanisms and develop cutting-edge technologies to overcome underlying genetic and functional aberrations. The establishment of the Centre of Excellence for the Technologies of Gene and Cell Therapy (CTGCT) at the National Institute of Chemistry (NIC) in Ljubljana represents a significant step forward, as it is the first centre of its kind in Slovenia. The CTGCT is poised to spearhead advances in cancer immunotherapy and personalised therapies for neurological and other rare genetic diseases.
View Article and Find Full Text PDFWomens Health Rep (New Rochelle)
December 2024
Hospital de Sant Pau, Barcelona, Spain.
Background: Heavy menstrual bleeding (HMB) is a common disorder interfering with physical, emotional and social domains, and overall quality of life (QoL). The Heavy Menstrual Bleeding-Visual Analog Scale (HMB-VAS) tool, including the VAS for menstrual bleeding intensity (VAS-Int) and the VAS for its interference with daily activities (VAS-Imp), is useful for HMB screening. The SAMANTA questionnaire (SAMANTA-Q) was developed and psychometrically validated in Spanish to easily identify women with HMB.
View Article and Find Full Text PDFExpert Opin Pharmacother
January 2025
Eye Clinic, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Introduction: Meibomian Gland Dysfunction (MGD) represents the most common cause of dry eye disease (DED). Traditional treatments mainly rely on heating and liquifying the meibum to favor its expression. However, recent knowledge advances have led to the development of novel therapies specifically designed for patients with MGD.
View Article and Find Full Text PDFNat Nanotechnol
January 2025
Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech College of Engineering and Emory School of Medicine, Atlanta, GA, USA.
The forward design of biosensors that implement Boolean logic to improve detection precision primarily relies on programming genetic components to control transcriptional responses. However, cell- and gene-free nanomaterials programmed with logical functions may present lower barriers for clinical translation. Here we report the design of activity-based nanosensors that implement AND-gate logic without genetic parts via bi-labile cyclic peptides.
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