AI Article Synopsis
- - Microscopic examination of esophageal biopsies is crucial for diagnosing eosinophilic esophagitis (EoE), focusing on eosinophil inflammation but also considering other abnormalities.
- - Pathology reports should include both peak eosinophil counts and other features before and after therapy.
- - Unlike esophageal strictures, the pathological changes found in EoE biopsies can be reversed with appropriate treatment.
Article Abstract
Microscopic examination of esophageal biopsies is essential to diagnose eosinophilic esophagitis (EoE). Eosinophil inflammation is the basis for the diagnosis, but additional abnormalities may contribute to persistent symptoms and epithelial barrier dysfunction. Both peak eosinophil count and assessments of additional features should be included in pre-therapy and post-therapy pathology reports. Pathologic abnormalities identified in esophageal biopsies of EoE are reversible in contrast to esophageal strictures.
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| http://dx.doi.org/10.1016/j.iac.2023.12.008 | DOI Listing |
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