AI Article Synopsis
- Rashes in newborns are common and usually harmless, but infections should be considered if there are pustules or vesicles, especially if the baby appears unwell or has risk factors for infections.
- Congenital cytomegalovirus can lead to serious issues like hearing loss and neurodevelopmental delays, with skin signs such as petechiae, while congenital syphilis shows up as copper-red lesions on the hands and feet that crust over time.
- Some rashes, like erythema toxicum neonatorum, are normal and temporary, while conditions like neonatal and infantile acne can differ, with milia being present at birth; transient changes like cutis marmor
Article Abstract
Rashes in the newborn period are common and most are benign. Infections should be suspected in newborns with pustules or vesicles, especially in those who are not well-appearing or have risk factors for congenital infection. Congenital cytomegalovirus infection can cause sensorineural hearing loss and neurodevelopmental delay. Skin manifestations of cytomegalovirus may include petechiae due to thrombocytopenia. The most common skin manifestations of early congenital syphilis are small, copper-red, maculopapular lesions located primarily on the hands and feet that peel and crust over three weeks. Erythema toxicum neonatorum and neonatal pustular melanosis are transient pustular rashes with characteristic appearance and distribution. Neonatal acne is self-limited, whereas infantile acne may benefit from treatment. Milia can be differentiated from neonatal acne by their presence at birth. Cutis marmorata and harlequin color change are transient vascular phenomena resulting from inappropriate or exaggerated dilation of capillaries and venules in response to stimuli.
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