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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11221371 | PMC |
| http://dx.doi.org/10.2217/nnm-2024-0080 | DOI Listing |
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Piezoelectric hydrogels for accelerating healing of diverse wound types.
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State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
The skin, as the body's largest organ, plays a crucial role in protecting against mechanical forces and infections, maintaining fluid balance, and regulating body temperature. Therefore, skin wounds can significantly threaten human health and cause a heavy economic burden on society. Recently, bioelectric fields and electrical stimulation (ES) have been recognized as a promising pathway for modulating tissue engineering and regeneration of wounded skin.
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Department of Electrical Engineering, Gachon University, Seongnam 13120, Republic of Korea.
In this study, in situ piezoelectricity was incorporated into the photoactive region to prepare a self-powered deep-ultraviolet photodetector based on a mixture of polyvinylidene fluoride (PVDF)@GaO and polyethyleneimine (PEI)/carbon quantum dots (CQDs). A ferroelectric composite layer was prepared using β-GaO as a filler, and the β-phase of PVDF was used as the polymer matrix. The strong piezoelectricity of β-PVDF can facilitate the separation and transport of photogenerated carriers in the depletion region and significantly reduce the dark current when the device is biased with an external bias, resulting in a high on/off ratio and high detection capability.
View Article and Find Full Text PDFSodium alginate based piezoelectric hydrogel for promoting healing of infected wounds at movable parts.
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Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, College of Life Science, Jilin Agricultural University, Changchun 130118, China. Electronic address:
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- * NNO-Gel can produce reactive oxygen species to kill bacteria when exposed to simulated sunlight and generates an electric field that stimulates cell migration and growth through movement.
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Sonodynamic therapy (SDT) utilizes specific sound waves to activate sonosensitizers, generating localized biological effects to eliminate tumor cells. With advancements in nanomedicine, the application of nano-acoustic sensitizers has significantly advanced the development of SDT. BaTiO (BTO), an inorganic nano-acoustic sensitizer, possesses light refraction characteristics and a high dielectric constant, and can generate an electric field under ultrasound (US) stimulation.
View Article and Find Full Text PDFPiezoelectric Stimulation Induces Osteogenesis in Mesenchymal Stem Cells Cultured on Electroactive Two-Dimensional Substrates.
ACS Appl Polym Mater
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Center for Biomaterials and Tissue Engineering (CBIT), Universitat Politècnica de València, Valencia 46022, Spain.
Article Synopsis
- Physical cues, such as piezoelectric stimulation, can effectively promote the osteogenic differentiation of mesenchymal stem cells (MSCs), mimicking the natural electroactive properties of bone.
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