Time-related ageing of the organism brings about the limitations to all human beings. The ageing process pertains to all organs and neither does it spare the brain, although, apart from neurodegenerative diseases, the changes in brain's functions seem to be less detectable. Many studies that were conducted for years in ageing adults provide evidence that lifestyle in which psychic and physical activity is maintained significantly and positively affects brain plasticity, i.e., normal ability to learn and develop, and therefore this lifestyle serves as a protective agent for cognitive functions even in the case of degenerative changes of brain tissue. Med Pr Work Health Saf. 2024;75(3):279-285.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.13075/mp.5893.01518 | DOI Listing |
J Clin Neurosci
January 2025
Faculty of Health and Medical Sciences, The University of Adelaide, Australia.
The Glasgow Coma Scale (GCS) was first published in The Lancet by Sir Graham Teasdale and Bryan Jennett 50 years ago based on their pioneering work on developing a numerical scale to describe coma in clear and reproducible terms and to avoid the confusion associated with the wide variety of descriptive terms for consciousness that were in use at the time. It's difficult to know if Teasdale and Jennett could have predicted how influential, widespread and long-lasting the GCS would become, but in retrospect it seems clear that the GCS was introduced at a perfect stage in the development of modern clinical neurosurgery and neuroscience research. The simplicity of the scale, its recognition by senior academics and the emerging radiology technologies in the 1970s heralded a new era of neuroscience and an approach to the management of not only traumatic brain injury (TBI) but other types of central nervous system disease in which consciousness was affected, such as aneurysmal subarachnoid haemorrhage and stroke.
View Article and Find Full Text PDFNeuropsychiatr Dis Treat
December 2024
Growth, Development and Mental Health Center of Children and Adolescents, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Chongqing, 400014, People's Republic of China.
Purpose: There is no consensus on whether cognitive measures among attention deficit hyperactivity disorder (ADHD) subtypes exhibit more similarities or differences, and most of them have been conducted on English-speaking subjects, lacking cross-cultural perspectives. The present study was aimed at investigating the intelligence structures of school-age children with ADHD who speak Chinese, using a multicenter and large sample size approach, offering some references for clinicians.
Patients And Methods: 772 children aged 6 to 12 years with ADHD took part in the cross-sectional study.
Nat Commun
January 2025
Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Genome editing using CRISPR-Cas systems is a promising avenue for the treatment of genetic diseases. However, cellular and humoral immunogenicity of genome editing tools, which originate from bacteria, complicates their clinical use. Here we report reduced immunogenicity (Red)(i)-variants of two clinically relevant nucleases, SaCas9 and AsCas12a.
View Article and Find Full Text PDFBrain Dev
December 2024
Professor of Neurology, School of Medicine, and Brain Institute (BraIns) Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil. Electronic address:
Imeta
December 2024
Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences Shenzhen China.
The Conference 2024 provides a platform to promote the development of an innovative scientific research ecosystem for microbiome and One Health. The four key components - Technology, Research (Biology), Academic journals, and Social media - form a synergistic ecosystem. Advanced technologies drive biological research, which generates novel insights that are disseminated through academic journals.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!