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A 14-step desensitization protocol for sebelipase alfa hypersensitivity in a patient with Wolman disease and secondary hemophagocytic lymphohistiocytosis.
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Endocrinology Unit, Department of Medicine, Selayang Hospital, Selangor, Malaysia.
Levothyroxine remains the standard therapy for patients with hypothyroidism worldwide. Levothyroxine allergy is rarely seen and alternative therapies are less efficacious and scarcely available. The use of liothyronine (LT3) monotherapy is less favoured due to its short half-life and unpredictable pharmacological profile.
View Article and Find Full Text PDFRapid subcutaneous desensitization for the management of delayed hypersensitivity reactions to omalizumab：A case report.
J Clin Pharm Ther
June 2019
Department of Allergy, Zhongnan Hospital of Wuhan University, Wuhan, China.
What Is Known And Objective: Omalizumab is effective as an add-on drug to treat severe persistent allergic asthma. However, delayed hypersensitivity reactions to omalizumab may deprive patients of its use. Rapid subcutaneous desensitization could be a solution.
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Department of Pharmacology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
Background: Drug hypersensitivity reactions to infliximab have been reported in pediatric patients. At times, these patients may need infliximab administration in spite of hypersensitivity. However, only a few reports of desensitization protocols are available in the literature in pediatric patients.
View Article and Find Full Text PDFThe lived experience: Nurses' experience of caring for patients with a traumatic spinal cord injury.
Int J Orthop Trauma Nurs
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Adelaide Nursing School, University of Adelaide, Australia.
Background: Nurses are involved in delivering care for patients following acute traumatic spinal cord injury throughout the entire care journey. An injury of this type is significant for the individual and their family and can be challenging for nurses delivering care for patients with life changing injuries, especially for nurses new to this setting. There is a lack of research that examines the experience of nurses caring for these patients in the acute setting.
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