AI Article Synopsis
- - The study aimed to investigate how maternal folic acid supplementation (FAS) during pregnancy affects childhood overweight, obesity, and body fat levels in a cohort of 1479 children evaluated at an average age of 6.4 years.
- - Results showed that maternal FAS was linked to a reduced risk of childhood overweight and lower body mass index (BMI) and body fat percentages, with significant associations noted particularly for children not breastfed and whose parents had lower education levels.
- - The findings suggest that taking folic acid during pregnancy may help lower the chances of childhood overweight and obesity, highlighting the importance of nutrition during pregnancy and its long-term effects on children's health.
Article Abstract
Objective: This study aimed to examine associations of maternal folic acid supplementation (FAS) during pregnancy with childhood overweight or obesity (OWO) or adiposity.
Methods: In a population-based cohort of 1479 children, maternal FAS during pregnancy was assessed retrospectively by questionnaires. BMI and body fat percentages were measured at a mean age of 6.4 years. Pertinent factors were accounted for in data analyses.
Results: Maternal FAS during pregnancy was negatively associated with OWO (adjusted odds ratio: 0.70; 95% CI: 0.50 to 0.99). There were inverse associations of maternal FAS during pregnancy with BMI z score (β: -0.22; 95% CI: -0.39 to -0.05), whole body fat percentage (β: -1.28; 95% CI: -2.27 to -0.30), trunk fat percentage (β: -1.41; 95% CI: -2.78 to -0.04), and limb fat percentage (β: -1.31; 95% CI: -2.32 to -0.30). Stratified analyses found inverse associations of FAS during pregnancy with OWO, BMI z score, and body fat percentages predominantly among children without breastfeeding and whose parents had a below-tertiary educational level.
Conclusions: This study provides novel evidence that maternal FAS during pregnancy was significantly associated with a decreased risk of childhood OWO and adiposity, particularly among children with no breastfeeding and lower parental educational level.
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| http://dx.doi.org/10.1002/oby.24012 | DOI Listing |
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