Clinical high risk for psychosis (CHR) is a transdiagnostic risk state. However, it is unclear how risk states such as CHR fit within broad transdiagnostic models such as the Hierarchical Taxonomy of Psychopathology (HiTOP). In this study, a hierarchical dimensional symptom structure was defined by unfolding factor analysis of self-report data from 3,460 young adults (=20.3). A subsample (n=436) completed clinical interviews, 85 of whom met CHR criteria. Regression models examined relationships between symptom dimensions, CHR status, and clinician-rated symptoms. CHR status was best explained by a reality distortion dimension, with contributions from internalizing dimensions. Positive and negative attenuated psychotic symptoms were best explained by multiple psychotic and nonpsychotic symptom dimensions including reality distortion, distress, fear, detachment, and mania. Attenuated psychotic symptoms are a complex presenting problem warranting comprehensive assessment. HiTOP can provide both diagnostic precision and broad transdiagnostic coverage, making it a valuable resource for use with at-risk individuals.
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http://dx.doi.org/10.1177/21677026221146178 | DOI Listing |
Psychol Res
December 2024
Department of Psychology, University of Almería, Almería, Spain.
Previous research highlights impairments in the recognition of facial expression of emotion in individuals diagnosed with Autism Spectrum Disorder (ASD). Relatives of people with ASD may exhibit similar, albeit subtler, impairments, referred to as the Broad Autism Phenotype (BAP). Recently, the Differential outcomes procedure (DOP) has been shown to enhance this ability in young adults using dynamic stimuli, with fewer intensity levels required to identify fear and surprise.
View Article and Find Full Text PDFJ Orthop Surg Res
December 2024
Teaching and Research Section of Clinical Nursing, Xiangya Hospital of Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
Objectives: This study aims to identify predictors of knee osteoarthritis (KOA) risk in middle-aged population, construct and validate a nomogram for KOA in this demographic.
Methods: From June to December 2020, we conducted a cross-sectional survey on 5,527 middle-aged individuals from Changsha and Zhangjiajie cities in Hunan Province, selected using a stratified multi-stage random sampling method. Data collection involved a structured questionnaire encompassing general demographic, physical condition, and lifestyle behaviors dimensions.
Zhonghua Wei Chang Wai Ke Za Zhi
December 2024
Department of General Surgery, General Hospital of Eastern Theater Command, PLA, Nanjing 210002, China.
To evaluate the safety, effectiveness, and long-term efficacy of the Jinling procedure for management of refractory mixed constipation. We prospectively collected clinical data of patients with refractory mixed constipation treated by the Jinling procedure in the Institute of General Surgery of our hospital from January 2007 to August 2023. Perioperative complications, effectiveness within 1 year of surgery (as assessed by the Wexner constipation score, gastrointestinal quality of life index, frequency of spontaneous defecation, rate of satisfactory defecation, body composition, serological indicators, defecography, anorectal manometry) and 10 years after surgery (as assessed by the Wexner constipation score, patient assessment of constipation symptom, SF-36 quality of life score, and questionnaire concerning satisfaction with defecation).
View Article and Find Full Text PDFPsych J
December 2024
Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran.
This study aimed to explore the mental health status of individuals seeking rhinoplasty before and 3 months after surgery. This study was conducted in 2022 at Velayat Hospital, involving patients aged 18-60 who were seeking rhinoplasty, selected using convenience sampling method. Exclusion criteria included prior nasal surgery and severe psychiatric disorders without clearance from a psychiatrist.
View Article and Find Full Text PDFJ Pain Symptom Manage
December 2024
West China School of Nursing, Sichuan University/West China Hospital, Sichuan University, Chengdu, China. Electronic address:
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