Background: () population plays a significant role in the spread of numerous diseases in urban environments. The present study is aimed at investigating the presence of (), , (), toxigenic, and in captured from urban areas of Tehran, Iran.

Methods: From October 2021 to October 2022, 100 urban rats were trapped in 5 different districts of Tehran, Iran. The genomic DNA was extracted from fecal samples, and the presence of , , , and species was evaluated using PCR assay. Moreover, PCR was used to assess the toxicity of isolates.

Results: Overall, 30% ( = 30/100) of fecal samples were positive for zoonotic pathogens. Based on the PCR on hippuricase (), glycine (), , and phospholipase C () genes, and were isolated from 18.2% ( = 14/77) and 5.2% ( = 4/77) of male rats. The highest frequency of and . was 25% ( = 5/20) related to the south of Tehran. Toxigenic was not detected in all regions.

Conclusion: According to the findings, rats are the main reservoirs for diseases. Therefore, rodent control coupled with the implementation of surveillance systems should be prioritized for urban health.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990632PMC
http://dx.doi.org/10.1155/2024/2929315DOI Listing

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