AI Article Synopsis
- - Research on precancers is crucial because early intervention is more effective for treatment, focusing on at-risk tissues and early lesions.
- - There is a need for risk stratification to avoid overtreatment, highlighting the importance of genetic and epigenetic aging in assessing risk levels.
- - Effective intervention and health policy strategies should integrate both macroenvironmental risk factors and the molecular and cellular aspects of lesions and at-risk tissues.
Article Abstract
Research on precancers, as defined as at-risk tissues and early lesions, is of high significance given the effectiveness of early intervention. We discuss the need for risk stratification to prevent overtreatment, an emphasis on the role of genetic and epigenetic aging when considering risk, and the importance of integrating macroenvironmental risk factors with molecules and cells in lesions and at-risk normal tissues for developing effective intervention and health policy strategies.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11170686 | PMC |
| http://dx.doi.org/10.1158/2159-8290.CD-23-1550 | DOI Listing |
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