Laparoscopic nerve lysis for deep endometriosis improves quality of life and chronic pain levels: A pilot study.

J Gynecol Obstet Hum Reprod

Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Published: September 2024

AI Article Synopsis

  • The study aimed to evaluate how surgical treatment affects pain management, analgesic use, and quality of life (QOL) for patients with endometriosis affecting pelvic nerves.
  • In a cohort of 21 patients who had laparoscopic neurolysis, most showed a significant reduction in chronic pain and decreased analgesic consumption post-surgery.
  • Results demonstrated that over half of the patients experienced improved QOL after the procedure, highlighting the potential benefits of surgical intervention for these patients.

Article Abstract

Objectives: To assess the benefit of surgical management of patients with endometriosis infiltrating pelvic nerves in terms of pain, analgesic consumption, and quality of life (QOL).

Methods: We conducted a retrospective cohort study In an Endometriosis referral center at a tertiary care university affiliated medical center. Patients diagnosed with endometriosis that underwent laparoscopic neurolysis for chronic pain were included. Patients rated their pain before and after surgery and differentiated between chronic pain and acute crises. Patients were requested to maintain a record of analgesic consumption and to evaluate their quality-of-life (QOL).

Results: Of the 21 patients in our study 15 (71.5 %) had obturator nerve involvement, 2 (9.5 %) had pudendal nerve involvement and 4 (19 %) had other pelvic nerve involvement. Median postoperative follow - up was of 8 months. All but 2 patients (9.6 %) had significant chronic pain improvement with a mean decrease of VAS of 3.05 (±2.5). Analgesic habits changed postoperatively with a significant decrease of 66 % of patients' daily consumption of any analgesics. Surgery improved QOL in 12 cases (57.1 %) and two patients (9.6 %) completely recovered with a high QOL.

Conclusion: Neurolysis and excision of endometriosis of pelvic nerves could results in significant improvement of quality of life.

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Source
http://dx.doi.org/10.1016/j.jogoh.2024.102778DOI Listing

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