AI Article Synopsis
- Anti-MDA5 antibody-positive dermatomyositis (DM) can lead to interstitial lung disease (ILD) and rare complications like pneumomediastinum, which is the presence of air in the mediastinum.
- A case was reported where a patient with DM-ILD experienced worsening symptoms, including hypotension and respiratory failure during treatment, due to increased subcutaneous and mediastinal emphysema.
- Timely intervention with mediastinal drainage through video-assisted thoracoscopic surgery significantly improved the patient's condition, highlighting the need for quick diagnosis and treatment of these serious complications.
Article Abstract
Anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM)-associated interstitial lung disease (ILD) can sometimes be complicated by pneumomediastinum, although tension pneumomediastinum is extremely rare. We herein report a case of anti-MDA5 antibody-positive DM-ILD that worsened subcutaneous and mediastinal emphysema during treatment. Hypotension and worsening respiratory failure were observed on day 20 of treatment. Mediastinal drainage under video-assisted thoracoscopic surgery promptly improved the patient's circulatory and respiratory status. Tension pneumomediastinum is a rare complication; however, it is a serious condition that may lead to hypotension or cardiac arrest and requires a prompt diagnosis and treatment.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671188 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.3418-23 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!