Complex skill learning depends on the joint contribution of multiple interacting systems: working memory (WM), declarative long-term memory (LTM) and reinforcement learning (RL). The present study aims to understand individual differences in the relative contributions of these systems during learning. We built four idiographic, ACT-R models of performance on the stimulus-response learning, Reinforcement Learning Working Memory task. The task consisted of short 3-image, and long 6-image, feedback-based learning blocks. A no-feedback test phase was administered after learning, with an interfering task inserted between learning and test. Our four models included two single-mechanism RL and LTM models, and two integrated RL-LTM models: (a) RL-based meta-learning, which selects RL or LTM to learn based on recent success, and (b) a parameterized RL-LTM selection model at fixed proportions independent of learning success. Each model was the best fit for some proportion of our learners (LTM: 68.7%, RL: 4.8%, Meta-RL: 13.25%, bias-RL:13.25% of participants), suggesting fundamental differences in the way individuals deploy basic learning mechanisms, even for a simple stimulus-response task. Finally, long-term declarative memory seems to be the preferred learning strategy for this task regardless of block length (3- vs 6-image blocks), as determined by the large number of subjects whose learning characteristics were best captured by the LTM only model, and a preference for LTM over RL in both of our integrated-models, owing to the strength of our idiographic approach.
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Lung Cancer
January 2025
Internal Medicine III, Wakayama Medical University, Wakayama, Japan.
Objectives: The lack of definitive biomarkers presents a significant challenge for chemo-immunotherapy in extensive-stage small-cell lung cancer (ES-SCLC). We aimed to identify key genes associated with chemo-immunotherapy efficacy in ES-SCLC through comprehensive gene expression analysis using machine learning (ML).
Methods: A prospective multicenter cohort of patients with ES-SCLC who received first-line chemo-immunotherapy was analyzed.
J Exp Child Psychol
January 2025
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, LMU Munich, 80336 München, Germany.
Early spelling depends on the ability to understand the alphabetic principle and to translate speech sounds into visual symbols (letters). Thus, the ability to associate sound-symbol pairs might be an important predictor of spelling development. Here, we examined the relation between sound-symbol learning (SSL) and early spelling skills.
View Article and Find Full Text PDFJ Contin Educ Health Prof
January 2025
Dr. Jacobs: Executive Director, Quality Catalyst Group, LLC, Minneapolis, MN. Dr. McCausland: Departments of Emergency Medicine and Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. Dr. McGowan: Chief Learning Officer and Co-Founder, ArcheMedX, Inc., Blue Bell, PA.
J Med Internet Res
January 2025
Department of Pediatrics, Medical School, University of Michigan, Ann Arbor, MI, United States.
Background: The mental health crisis among college students intensified amid the COVID-19 pandemic, suggesting an urgent need for innovative solutions to support them. Previous efforts to address mental health concerns have been constrained, often due to the underuse or shortage of services. Mobile health (mHealth) technology holds significant potential for providing resilience-building support and enhancing access to mental health care.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Department of Health Promotion and Health Education, College of Education, National Taiwan Normal University, Taipei, Taiwan.
Background: Chronic kidney disease (CKD) imposes a significant global health and economic burden, impacting millions globally. Despite its high prevalence, public awareness and understanding of CKD remain limited, leading to delayed diagnosis and suboptimal management. Traditional patient education methods, such as 1-on-1 verbal instruction or printed brochures, are often insufficient, especially considering the shortage of nursing staff.
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