AI Article Synopsis
- Normalization of echocardiographic measurements based on body surface area can misclassify patients with obesity or sarcopenia, highlighting the need for better alternative normalization methods.
- A study involving 3032 individuals assessed echocardiographic parameters, focusing on a subgroup of 608 without cardiopulmonary diseases to derive normative values based on various body size indexation methods.
- The findings indicate that body surface area and height provided more consistent results across different racial and ethnic groups, with height showing the least variability between sexes.
Article Abstract
Background: Normalization of echocardiographic chamber measurements for body surface area may result in misclassification of individuals with obesity or sarcopenia. Normalization for alternative measures of body size may be preferable, but there remains a dearth of information on their normative values and association with cardiovascular function metrics.
Methods And Results: A total of 3032 individuals underwent comprehensive 2-dimensional echocardiography at Exam 6 in MESA (Multi-Ethnic Study of Atherosclerosis). In the subgroup of 608 individuals free of cardiopulmonary disease (69.5±7.0 years, 46% male, 48% White, 17% Chinese, 15% Black, 21% Hispanic), normative values were derived for left and right cardiac chamber measurements across a variety of ratiometric (body surface area, body mass index, height) and allometric (height, height) scaling parameters. Normative upper and lower reference values were provided for each scaling parameter stratified across age groups, sex, and race or ethnicity. Among scaling parameters, body surface area and height were associated with the least variability across race and ethnicity categories and height was associated with the least variability across sex categories.
Conclusions: In this diverse cohort of community-dwelling older adults, we provide normative values for common echocardiographic parameters across a variety of indexation methods.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262507 | PMC |
| http://dx.doi.org/10.1161/JAHA.123.034029 | DOI Listing |
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