AI Article Synopsis
- Tuberculosis destroyed lung poses a major global health issue, and this study aimed to uncover its risk factors among patients with pulmonary tuberculosis and other lung diseases.
- Conducted from January 2019 to December 2021, the case-control study included 341 patients, with 182 cases of tuberculosis destroyed lung identified, and utilized binary logistic regression to analyze the data.
- Key risk factors identified were older age (46-60 and >60 years), previous TB treatment, malnutrition, respiratory failure, and bronchiarctia, while a normal or overweight BMI offered protective effects against the condition.
Article Abstract
Background: Tuberculosis destroyed lung constitutes a significant worldwide public health challenge, little is known about its associated risk factors and prognosis. Our study aimed to identify the risk factors of tuberculosis destroyed lung among pulmonary tuberculosis and structural lung diseases.
Methods: Between January 2019 and December 2021, a case-control study was conducted at the Third People's Hospital of Shenzhen in China. We collected the clinical data among patients with pulmonary tuberculosis and structural lung diseases. Cases were defined as patients with tuberculosis destroyed lung. Controls were not diagnosed with the tuberculosis destroyed lung. A binary logistic regression was performed.
Results: In our study, a total of 341 patients met the inclusion criteria, including 182 cases and 159 controls. We found that age ranges of 46-60 years (aOR: 4.879; 95% CI: 2.338-10.180), >60 years (aOR: 3.384; 95% CI: 1.481-7.735); history of TB treatment (aOR: 2.729; 95% CI: 1.606-4.638); malnutrition (aOR: 5.126; 95% CI: 1.359-19.335); respiratory failure (aOR: 5.080; 95% CI: 1.491-17.306); and bronchiarctia (aOR: 3.499; 95% CI: 1.330-9.209) were the independent risk factors for tuberculosis destroyed lung. Conversely, having a normal (aOR: 0.207; 95% CI: 0.116-0.371) or overweight BMI (aOR: 0.259; 95% CI: 0.090-0.747) emerged as a protective factor against tuberculosis destroyed lung.
Conclusion: This study indicated that tuberculosis destroyed lung is a common condition among patients with pulmonary tuberculosis and structural lung diseases. The independent risk factors for tuberculosis destroyed lung were identified as being within the age groups of 46-60 and over 60 years, having a previous history of TB treatment, malnutrition, respiratory failure, and bronchiarctia. It is essential to closely monitor patients possessing these risk factors to prevent the progression towards tuberculosis destroyed lung.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10985215 | PMC |
| http://dx.doi.org/10.2147/RMHP.S448765 | DOI Listing |
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Article Synopsis
- The study focuses on differentiating non-tuberculous mycobacteria pulmonary disease (NTM-PD) from pulmonary tuberculosis (PTB) in patients with positive sputum smear results, identifying clinical characteristics of both diseases over a span of four years in China.
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Destroyed lung syndrome is a recognized devastating complication of pulmonary tuberculosis (TB) that affects the quality of life of patients. Clinicians in TB-endemic countries should be aware of this complication aiming at prevention. TB control programs should intensify efforts at early detection and treatment and also provide interventions for post-TB complications.
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