Because the β-lactam ring has a molecular structure similar to that of gamma-aminobutyric acid (GABA) neurotransmitters, it binds to GABA A receptors and inhibits GABAergic transmission, causing AAE. The possibility of antimicrobial-associated encephalopathy should be considered in cases of neurological or psychiatric symptoms after initiating an antimicrobial regimen.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10985933 | PMC |
| http://dx.doi.org/10.1002/ccr3.8665 | DOI Listing |
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