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Correction: Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E.
J Exp Clin Cancer Res
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The National Engineering Laboratory for Anti-Tumor Protein Therapeutics, Tsinghua University, Beijing, 100084, China.
The baby duck syndrome as cognitive bias in user-interface interaction.
Cogn Process
December 2024
Department of Psychology, National Research University Higher School of Economics, Moscow, Russia.
As technological interfaces are relatively new cultural tools, regular interaction can lead to new psychological phenomena, like the baby duck syndrome, where users favor old interfaces over updates. This syndrome is seen as a cognitive bias in human-computer interaction. Two studies were conducted: Study 1 on an Airbnb app (old vs.
View Article and Find Full Text PDF[Research progress of colonic electrical stimulation in the treatment of chronic constipation].
Zhonghua Wei Chang Wai Ke Za Zhi
December 2024
Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College Huazhong University of Science and Technology, Wuhan430022, China.
Chronic constipation refers to a reduction in the frequency of bowel movements and difficulty in defecation lasting for more than 6 months, with a comprehensive incidence rate of 15% in the population. Chronic constipation is a significant health concern that greatly affects the quality of life of patients and results in substantial healthcare resource consumption. Current common treatment strategies include lifestyle modifications, pharmacological therapy, biofeedback therapy, enemas, and surgical procedures, but the effectiveness of these approaches remains limited.
View Article and Find Full Text PDF[Surgical treatment for intractable constipation: selection of procedure and perioperative management].
Zhonghua Wei Chang Wai Ke Za Zhi
December 2024
Department of General Surgery, General Hospital of Eastern Theater Command, PLA, Nanjing 210002, China.
When chronic constipation develops to the stage of intractable constipation, the symptoms of constipation in patients are severe and persistent, and drug treatment is often ineffective, so surgical treatment is often considered. The clinical manifestations of patients with intractable constipation are variable, and the underlying pathophysiological changes involve various abnormal and dysfunctional anatomical structure of colorectal and pelvic floor, which are different. For the surgical treatment of intractable constipation, accurate preoperative classification diagnosis is very important, and it is necessary to formulate an exact and effective surgical plan to avoid untargeted empirical treatment.
View Article and Find Full Text PDFSelective laser sintering for printing bilayer tablets.
Int J Pharm
December 2024
Delta Pharmaceutics Ltd., Chatham, Kent ME4 4TB, UK; Centre for Research Innovation (CRI), University of Greenwich, Chatham ME4 4TB, UK. Electronic address:
In this study Selective Laser Sintering (SLS) was used to produce bilayer tablets containing rosuvastatin and acetylsalicylic acid. Initially, monolithic tablets of each drug were manufactured using different laser intensities in order to identify their impact on the tablet's dissolution, friability and hardness. After the optimization, the final bilayer tablet was fabricated using a new method, that allowed the printing using different powder blends.
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