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[Solid-phase extraction coupled with high performance liquid chromatography-triple quadrupole mass spectrometry for simultaneous determination of seven coumarins in water samples from drinking water treatment plants].
Se Pu
January 2025
School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Chlorinated coumarins, which are as cytotoxic as highly toxic halobenzoquinones toward CHO-K1 cells, have recently been identified as disinfection byproducts in drinking water disinfection processes. Therefore, detecting coumarins in water samples collected at various stages from drinking water treatment plants helps assess the formation of chlorinated coumarins in drinking water. Hence, a simple, rapid, accurate, and sensitive method for quantifying coumarins in water samples is required.
View Article and Find Full Text PDFCyanobacteria Boring Limestones in Freshwater Settings-Their Pioneering Role in Sculpturing Pebbles and Carbonate Dissolution.
Geobiology
December 2024
Department of Geography and Geology, Institute of Geological Sciences, Jagiellonian University, Kraków, Poland.
In freshwater lakes and rivers, cyanobacteria belonging to the family Leptolyngbyaceae bore > 1 mm deep into limestone pebbles by dissolving carbonate at the tip of their 3-8 μm-thick filaments. The abundance of these borings decreases downward while it is so high at the rock surface that micrometric debris is formed. Moreover, the disintegrated material on the pebbles' surface can be easily removed, for instance, when pebbles are grinding against each other due to wave or current action or when insect larvae settle and scratch loosened grains from the surface while constructing their cases.
View Article and Find Full Text PDFInvestigation of the molecular mechanism of quercetin in inhibiting ankylosing spondylitis ossification via the bone morphogenetic protein/smad signaling pathway.
Med Mol Morphol
December 2024
Graduate School, Tianjin Medical University, Tianjin, 300070, China.
Ankylosing spondylitis (AS) is a chronic inflammatory disease involving the spine and bone joints, which is characterized by hyperosteogeny, ossification of ligaments, and ankylosis. Quercetin is a natural polyphenolic compound with various biological activities such as antioxidant, anti-inflammatory, and anti-tumor. It was to explore the effect of quercetin on AS ossification and its molecular mechanism.
View Article and Find Full Text PDFLiver Function Biomarkers and Lung Cancer Risk: A Prospective Cohort Study in the UK Biobank.
Clin Respir J
December 2024
Department of Radiation Oncology, Yunfu People's Hospital, Yunfu, China.
Background: As the primary organ of metabolism and detoxification, the liver may contribute to the pathogenesis of lung cancer. We aimed to illuminate the intricate link between liver function biomarkers and lung cancer risk, as well as delineate the role of smoking behavior within this association.
Methods: We investigated the associations of seven liver function biomarkers levels (alkaline phosphatase [ALP], alanine transaminase [ALT], total bilirubin [TBIL], albumin [ALB], gamma-glutamyltransferase [GGT], aspartate transaminase [AST], and total protein [TP]) with lung cancer risk across the UK Biobank (N = 337 499) through restricted cubic splines and Cox proportional hazards models.
Osteogenic Induction Activity of Magnesium Chloride on Human Periodontal Ligament Stem Cells.
Int Dent J
December 2024
Center of Excellence for Dental Stem Cell Biology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand; Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. Electronic address:
Objectives: Periodontal ligament stem cells (PDLSCs) are promising for regenerative therapies due to their self-renewal and multilineage differentiation, essential for periodontal tissue repair. Although magnesium plays a vital role in bone metabolism, its specific effects on PDLSCs and potential applications in regeneration are unclear. This study aimed to investigate the effects of magnesium chloride (MgCl₂) on the proliferation and osteogenic differentiation of human PDLSCs (hPDLSCs).
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