A corneal stroma circular ring has captured by smartphone adaptor slit lamp camera after smile for 1 week.
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| http://dx.doi.org/10.1002/ccr3.8690 | DOI Listing |
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Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction.
Ann Med
December 2025
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Objective: To evaluate the longitudinal changes in the effective optical zone (EOZ) following hyperopic keratorefractive lenticule extraction (KLEx) and investigate factors influencing the EOZ.
Patients And Methods: This retrospective study included 27 patients who underwent hyperopic KLEx. According to the transition zone (TZ) sizes, they were divided into two groups: group A (21 eyes) with a 2.
Digital light processing 3D bioprinting of biomimetic corneal stroma equivalent using gelatin methacryloyl and oxidized carboxymethylcellulose interpenetrating network hydrogel.
Biofabrication
January 2025
Division of Engineering, New York University Abu Dhabi, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates, Abu Dhabi, 129188, UNITED ARAB EMIRATES.
Corneal blindness, a leading cause of visual impairment globally, has created a pressing need for alternatives to corneal transplantation due to the severe shortage of donor tissues. In this study, we present a novel interpenetrating network hydrogel composed of gelatin methacryloyl (GelMA) and oxidized carboxymethyl cellulose (OxiCMC) for bioprinting a biomimetic corneal stroma equivalent. We tested different combinations of GelMA and OxiCMC to optimize printability and subsequently evaluated these combinations using rheological studies for gelation and other physical, chemical, and biological properties.
View Article and Find Full Text PDFBiochemical components of corneal stroma: a study on myopia classification based on Raman spectroscopy and deep learning methods.
Biomed Opt Express
January 2025
Center for Biomedical-photonics and Molecular Imaging, Advanced Diagnostic-Therapy Technology and Equipment Key Laboratory of Higher Education Institutions in Shaanxi Province, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710126, China.
The study aimed to identify differences in the biochemical composition of corneal stroma lenses across varying degrees of myopia using Raman spectrum characteristics. Corneal stroma lens samples from 38 patients who underwent small incision lens extraction (SMILE) surgery, were categorized into low (n = 9, spherical power -3.00D), moderate (n = 23, spherical power < -3.
View Article and Find Full Text PDFRefractive Changes and Corneal Thickness in Healthy Mountaineers at High Altitude: The Korzhenevskoi Experience (7105 m).
Cornea
January 2025
Department of Ophthalmology, Rothschild Foundation, Paris, France; and.
Purpose: The purpose of this study was to investigate the effect of hypoxia and hypobaric conditions on refraction and central corneal thickness on healthy corneas during an ascent without oxygen supplementation above 7000 m (23 000 ft).
Methods: Twelve multinational mountaineers were included in a prospective observational cohort study during an expedition to the Korzhenevskoi Peak (7105 m). The two patients excluded from the study had a history with keratoconus or were current wearers of rigid contact lenses.
A case of corneal opacity caused by atovaquone administration.
Am J Ophthalmol Case Rep
March 2025
Department of Ophthalmology and Visual Sciences, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki City, Nagasaki, 852-8501, Japan.
Purpose: Atovaquone is an alternative drug that is used for the prevention and treatment of pneumonia when the first-line drug, sulfamethoxazole-trimethoprim (ST combination), cannot be used due to side effects. However, atovaquone is known to cause ocular side effects including oculomucocutaneous syndrome and vortex keratopathy. In this report, we describe a patient who developed bilateral white granular diffuse corneal opacity that extended from the corneal sub-epithelium to the stroma after continuous oral atovaquone administration for 14 months.
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