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Oral Cyclophosphamide for Patients With Metastatic Castration-Resistant Prostate Cancer in a Scenario of Limited Health Care Resources.
JCO Glob Oncol
January 2025
Genitourinary Medical Oncology Service, Instituto do Câncer do Estado de São Paulo (ICESP), University of São Paulo, São Paulo, Brazil.
Purpose: Prior noncontemporary studies showed that oral cyclophosphamide is an active treatment of metastatic castration-resistant prostate cancer (mCRPC). However, cyclophosphamide is currently underutilized in routine clinical practice given the lack of survival benefit and the emergence of more effective treatments.
Methods: We retrospectively reviewed our institutional database to identify patients with mCRPC treated with cyclophosphamide.
Sacral Alar-Iliac (SAI) screw diameter is not associated with pelvic fixation failure for neuromuscular scoliosis patients.
Spine Deform
January 2025
Jackie and Gene Autry Children's Orthopedic Center, Children's Hospital Los Angeles, 4650 Sunset Blvd, MS69, Los Angeles, CA, 90027, USA.
Purpose: Determine if Sacral Alar-Iliac (SAI) screw diameter is associated with pelvic fixation failure in pediatric patients with neuromuscular scoliosis (NMS) treated with posterior spinal fusion (PSF).
Methods: NMS patients from a single institution who underwent PSF with bilateral SAI screw fixation from 2010 to 2021 were retrospectively reviewed. Clinical parameters, SAI screw sizes, and radiographic outcomes were analyzed.
Symmetry in the developmental stages of permanent human teeth: a comparative study between maxilla and mandible.
Eur Arch Paediatr Dent
January 2025
Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Turner Street, London, E1 2AD, UK.
Objective: The aim of this study was to assess symmetry of developmental stage of permanent teeth between the left and right side of the jaw, as well as between the maxilla and the mandible.
Methods: A sample of 150 panoramic radiographs of individuals aged 6-20 years (69 males, 81 females) were selected from an open-access radiographic collection (Maxwell Museum of Anthropology's orthodontic collection, Albuquerque, USA). All developing immature permanent teeth (n = 489) were scored by the first author using Moorrees and Demirjian tooth stages.
Background: Rearranged during transfection () fusions represent a distinct molecular subset of non-small cell lung cancer (NSCLC) with targeted therapeutic potential. Selpercatinib, a highly selective inhibitor, has demonstrated efficacy in various solid tumors harboring alterations. Here, we present a case highlighting the use and clinical outcomes of selpercatinib in a patient diagnosed with advanced lung adenocarcinoma harboring a fusion.
View Article and Find Full Text PDFHealing the Open Apex: A Case Report on Innovative Apexogenesis of a Maxillary Molar Using Bio-C Repair.
Cureus
December 2024
Department of Conservative Dentistry and Endodontics, The Oxford Dental College, Bengaluru, IND.
Preserving pulp vitality in developing permanent teeth is paramount. This approach facilitates continued root formation, ultimately leading to apical closure, enhanced root strength, and improved overall tooth integrity. This case report details the management of a 17-year-old female patient presenting with dental caries on the right permanent maxillary molar.
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