Invasive aspergillosis (IA) is the most severe type of infection. Yunnan has developed agriculture, and the proportion of triazole-resistant induced by triazole fungicides is much higher than that in other regions of China. Inhalation of triazole-resistant is one of the main factors inducing IA. We gathered five strains of from the sputum or bronchoalveolar lavage fluid (BALF) of patients with IA in Yunnan. Subsequent testing showed that all of these strains were resistant to triazoles and harboured mutations in the tandem repeat sequence of the promoter region, suggesting that they may be triazole-resistant present in the environment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10976991PMC
http://dx.doi.org/10.1080/21501203.2023.2299472DOI Listing

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