AI Article Synopsis

  • Waterhouse-Friderichsen syndrome (WFS) is a rare and serious condition linked to severe adrenal gland damage, mainly due to meningococcal infections.
  • A case involving a 62-year-old woman with HIV/AIDS and substance misuse illustrates the complexities of diagnosing WFS, especially in patients with multiple health issues.
  • Effective treatment requires careful management of steroids and vasopressors and emphasizes the importance of quick diagnosis and intervention to reduce the high risk of death from this syndrome.

Article Abstract

Waterhouse-Friderichsen syndrome (WFS) is a rare but life-threatening complication associated with acute hemorrhagic necrosis of the adrenal glands, primarily linked to meningococcal infection. This report details the case of a 62-year-old female with HIV/AIDS and substance misuse who presented with ventricular tachycardia and hemodynamic instability. Subsequent evaluation revealed WFS in the context of disseminated meningococcal infection. The case highlights the diversity of WFS manifestations and the diagnostic challenges, particularly in patients with comorbidities. Managing WFS involves a delicate balance of steroids and vasopressors, necessitating a multidisciplinary approach. Timely diagnosis and intervention are critical in mitigating the high mortality associated with this syndrome.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10978463PMC
http://dx.doi.org/10.7759/cureus.55093DOI Listing

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