The National Confidential Enquiry into Patient Outcome and Death reviewed the quality of physical healthcare provided to adults admitted to a mental health inpatient setting, highlighting areas of practice that need improving and making recommendations for clinical and organisational changes that will improve patient care.
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| http://dx.doi.org/10.12968/hmed.2023.0440 | DOI Listing |
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Exercise and exerkines: Mechanisms and roles in anti-aging and disease prevention.
Exp Gerontol
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Shanghai anti-doping Laboratory, Shanghai University of Sport, Shanghai 200438, China; Department of Rheumatology and Immunology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:
Aging is a complex biological process characterized by increased inflammation and susceptibility to various age-related diseases, including cognitive decline, osteoporosis, and type 2 diabetes. Exercise has been shown to modulate mitochondrial function, immune responses, and inflammatory pathways, thereby attenuating aging through the regulation of exerkines secreted by diverse tissues and organs. These bioactive molecules, which include hepatokines, myokines, adipokines, osteokines, and neurokines, act both locally and systemically to exert protective effects against the detrimental aspects of aging.
View Article and Find Full Text PDFRapid indirect detection of N-lactoyl-phenylalanine using dual DNA biosensors based on solution-gated graphene field-effect transistor.
Biosens Bioelectron
January 2025
School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, 230009, China; Engineering Research Center of Bio-process, Ministry of Education, Hefei University of Technology, Hefei, 230009, China. Electronic address:
As obesity rates continue to rise, there is an increasing focus on reducing obesity through exercise. People are becoming more aware of the importance of weight loss through physical activity. However, the effectiveness of exercise can vary significantly among individuals, making it challenging to evaluate its impact.
View Article and Find Full Text PDF'Entanglement of nursing care': A theoretical proposition to understand the complexity of nursing work and division of labour.
Int J Nurs Stud
January 2025
NIHR Collaboration for Applied Research (Wessex), University of Southampton, Southampton, United Kingdom. Electronic address:
Ongoing challenges in the provision of care, driven by growing care complexity and nursing shortages, prompt us to reconsider the basis for efficient division of nursing labour. In organising nursing work, traditionally the focus has been on identifying nursing tasks that can be delegated to other less expensive and less highly educated staff, in order to make best use of scarce resources. We argue that nursing care activities are connected and intertwined.
View Article and Find Full Text PDFCognitive function differs across healthy lifestyle behavior profiles: a 10-year population-based prospective cohort study.
J Nutr Health Aging
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Department of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. Electronic address:
Background: Modifiable lifestyle behaviors significantly influence the risk of cognitive impairment. However, the cumulative effects of multidimensional lifestyle profiles on cognitive function remain poorly understood, as most studies examine individual lifestyle behaviors in isolation. This study aimed to identify distinct profiles of individuals based on healthy lifestyle behaviors and to examine associations between these profiles and cognitive function in older Chinese adults.
View Article and Find Full Text PDFIntensive interdisciplinary specialized rehabilitation or regular physiotherapy for multiple sclerosis? A randomised controlled trial with economic evaluation.
Ann Phys Rehabil Med
January 2025
Physical and Rehabilitation medicine Department, Raymond Poincaré Hospital, GHU Paris Saclay, APHP, 104 Bld Raymond Poincaré, Garches, France; End: icap laboratory, Inserm Unit 1179, UVSQ, 2 Av. de la Source de la Bièvre, Montigny-le-Bretonneux, France.
Background: The benefits of Interdisciplinary Rehabilitation in an Outpatient Specialised Unit (IROSU) have not been determined.
Objectives: To compare the effects of IROSU and physiotherapy in the community on impairment, function and Quality Of Life (QoL) in people with Multiple Sclerosis (pwMS) and to determine the medico-economic impact.
Methods: Pragmatic, multicentre, parallel, randomized (centralised computer-generated randomisation) controlled trial.
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