Tularaemia is a highly infectious, zoonotic disease caused by , which has become increasingly prevalent over the past decade. Depending on the route of infection, different clinical manifestations can be observed. We report a case of typhoidal tularaemia presenting as a febrile illness with gastrointestinal symptoms in a patient in her mid-80s. During the acute illness phase and in the context of alcohol-related liver cirrhosis, the patient developed progressive ascites. During paracentesis, spontaneous bacterial peritonitis was consistently reported. Blood culture revealed Gram-negative bacilli identified as upon microscopic examination. Immediate clinical improvement was observed after adaptation to a pathogen-specific antibiotic regime. Typhoidal tularaemia presents general, non-specific symptoms without the local manifestations seen in other forms of the disease, thus representing a diagnostic challenge. In the case of protracted fever and if the epidemiological context as well as possible exposure are compatible, tularaemia should be considered in the differential diagnosis.
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http://dx.doi.org/10.1136/bcr-2023-256509 | DOI Listing |
BMJ Case Rep
March 2024
Departement of Infectiology, University and Hospital of Fribourg, Fribourg, Switzerland.
Tularaemia is a highly infectious, zoonotic disease caused by , which has become increasingly prevalent over the past decade. Depending on the route of infection, different clinical manifestations can be observed. We report a case of typhoidal tularaemia presenting as a febrile illness with gastrointestinal symptoms in a patient in her mid-80s.
View Article and Find Full Text PDFFront Microbiol
January 2024
Centre National de Référence Francisella tularensis, CHU Grenoble Alpes, Grenoble, France.
Tularemia is a zoonosis caused by the Gram negative, facultative intracellular bacterium . This disease has multiple clinical presentations according to the route of infection, the virulence of the infecting bacterial strain, and the underlying medical condition of infected persons. Systemic infections (e.
View Article and Find Full Text PDFVet Q
December 2023
Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Tularemia caused by Gram-negative, coccobacillus bacterium, is a highly infectious zoonotic disease. Human cases have been reported mainly from the United States, Nordic countries like Sweden and Finland, and some European and Asian countries. Naturally, the disease occurs in several vertebrates, particularly lagomorphs.
View Article and Find Full Text PDFIDCases
June 2023
Department of Medicine, Division of Infectious Diseases, University of Missouri Hospital and Clinic, 1 Hospital Dr, Columbia, MO 65212, USA.
Mikrobiyol Bul
October 2022
Sivas Cumhuriyet University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sivas, Türkiye.
Tularemia is a zoonotic bacterial infectious disease caused by a gram-negative coccobacillus namely Francisella tularensis. In humans, disease leads to several different clinical forms (ulceroglandular, glandular, oculoglandular, respiratory, typhoidal and oropharyngeal). Since the main mode of transmission of the disease to humans in Türkiye is by drinking water contaminated with F.
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