Introduction: Schizophrenia and autism spectrum disorder are distinct neurodevelopmental disorders sharing clinically relevant behaviours. However, early sensory responses show divergent responses. Individuals with schizophrenia typically exhibit cortical whereas individuals with autism show cortical . Identifying reliable neurobiological differences between the disorders can diminish misdiagnosis and optimise treatments.
Methods: The pattern glare test (PGT) is a simple measure of behavioural hyperexcitability. It measures the number of illusions seen in a static horizontal grating. We collected PGT data from non-clinical adults varying in traits of autism and schizophrenia (schizotypy). 576 undergraduate students completed an online survey consisting of the Schizotypal Personality Questionnaire - Brief Revised, the Autism Spectrum Quotient, and the PGT.
Results: Subclinical autism and schizotypy traits were highly correlated. However, only schizotypy scores were significantly predictive of reporting more pattern glare (PG) illusions. When assessing the subcomponents of the schizotypy and autism scores, positive and disorganised schizotypy traits were predictive of reporting more PG illusions. Whereas, subclinical autism factors were not predictive of PG illusions.
Conclusions: High schizotypy performed the PGT in a manner consistent with behavioural hyperexcitability. The PGT distinguished subclinical autistic traits from schizotypy, suggesting potential clinical application.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11296901 | PMC |
| http://dx.doi.org/10.1080/13546805.2024.2335103 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Unique Retinoscopic Reflex Pattern in the Initial Stages of Keratoconus and Its Clinical Significance for Early Keratoconus Detection: A Case Report.
Cureus
November 2024
Department of Optometry, Noor Alyemen Eye and E.N.T Consulting Center, Sana'a, YEM.
Keratoconus is a bilateral eye anomaly in which the cornea develops gradually, becoming steeper and thinner, causing irregular astigmatism and myopia. This unique case report highlights an atypical retinoscopic reflex that can be observed in the initial stages of keratoconus. While the reflex deviates subtly from the normal form, exhibiting a slightly distorted, irregular, and non-scissoring pattern, it differs significantly from the well-documented "scissor reflex," which is characteristic of moderate to advanced stages.
View Article and Find Full Text PDFThe Prevalence and Severity of Computer Vision Syndrome Among Primary Care Health Workers in the Ministry of National Guard Health Affairs, Central Region, Saudi Arabia.
Cureus
November 2024
Family Medicine and Primary Care Department, King Abdulaziz Medical City Riyadh, Riyadh, SAU.
Background Computer vision syndrome (CVS) is a common condition affecting individuals who spend prolonged periods using electronic devices. It is characterized by symptoms such as eye strain, dryness, headaches, and neck pain. This study aims to assess the prevalence of CVS symptoms among healthcare professionals, their awareness of the condition, and the effectiveness of various preventative practices.
View Article and Find Full Text PDFSensitization and Habituation of Hyper-Excitation to Constant Presentation of Pattern-Glare Stimuli.
Neurol Int
November 2024
School of Computer Science, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Background/objectives: Pattern glare, associated with cortical hyperexcitability, induces visual distortions and discomfort, particularly in individuals susceptible to migraines or epilepsy. While previous research has primarily focused on transient EEG responses to patterned stimuli, this study aims to investigate how continuous presentation of pattern-glare stimuli affects neural adaptation over both fine (seconds) and coarse (entire experiment) temporal scales.
Methods: EEG recordings were obtained from 40 healthy participants exposed to horizontal square-wave gratings at three spatial frequencies presented continuously for three seconds each across multiple trials.
Purpose: To evaluate range of visual acuity, visual quality, and safety of the IC-8 small-aperture (SA) intraocular lens (IOL) (Apthera; Bausch & Lomb, Inc) in patients with cataract.
Methods: This was a prospective, multicenter, open-label, parallel-group, non-randomized, examiner-masked, 12-month clinical study conducted at 21 sites in the United States. Included patients (N = 453) received either the SA IOL (targeted to -0.
Efficacy of an mHealth intervention to support pain self-management and improve analgesia in patients with rib fractures: protocol for a randomised controlled trial.
BMJ Open
November 2024
Pain Management Research Institute, Kolling Institute, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Introduction: In light of the risks of over-reliance on opioid analgesia during recovery from rib fractures, there is increased interest in the efficacy of non-pharmacological approaches to pain management. This paper describes the protocol for a double-blind randomised controlled trial to evaluate the efficacy of an mHealth intervention for reducing pain intensity, pain-related distress and opioid use during early recovery from rib fractures.
Methods And Analysis: Adults (N=120) with isolated rib fractures will be recruited within 24 hours of admission to a large public hospital in Sydney, Australia (single site), and randomised (1:1 allocation) to an intervention or active control group.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!